ChemicalBook CAS DataBase List 5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-

5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]- synthesis

9synthesis methods

Product Name:5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-
CAS Number:330785-84-7
Molecular formula:C18H21ClN4O4
Molecular Weight:392.84

41965-95-1 Synthesis

3-CHLORO-4-METHOXYBENZYLAMINE HYDROCHLORIDE

41965-95-1
262 suppliers
$15.00/1 g

5-PyriMidinecarboxylic acid, 4-[[(3-chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)- 1-pyrrolidinyl]-

330785-84-7
110 suppliers
$80.00/250mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: triethylamine / tetrahydrofuran / 0.25 h / 20 °C / Cooling with ice
1.2: 20 °C
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 20 °C / Cooling with ice
3.1: triethylamine / dichloromethane / 3 h / 20 °C / Cooling with ice
4.1: sodium hydroxide; water / methanol

References:

330785-81-4 Synthesis