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ChemicalBook CAS DataBase List 4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE

4-(2-KETO-1-BENZIMIDAZOLINYL)PIPERIDINE synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 16 h / 80 °C
2: palladium 10% on activated carbon; ammonium formate / methanol / 1 h / 60 °C
3: triethylamine / dichloromethane / 0.5 h / 20 °C
4: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

References:

Tierxi (Nanjing) Pharmaceutical Research And Development Co., Ltd.;Chu Wen;Liu Chun;Wang Zhongyi CN104829591, 2017, B

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