Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 6-METHYLAMINOURACIL
34284-87-2

6-METHYLAMINOURACIL synthesis

4synthesis methods
-

Yield:34284-87-2 76%

Reaction Conditions:

for 2 h;Reflux;

Steps:

General Procedure for Synthesis of 6-N-arylaminouracils 2a-h

General procedure: 6-Chlorouracil (0.2 g, 1.36 mmol) and appropriateamines (0.03 mol) were heated to reflux for 2 h. The mixturewas then cooled and Et2O was added. The mixture was sonicatedfor 15 min. The white suspension was filtered andwashed with water (15 mL), methanol (15 mL) and Et2O (15mL). The white solid was placed in a desiccator and driedovernight to yield 2a-h.

References:

Dou, Xiaoxue;Li, Xin;Tao, Liu;Hu, Chunqi;Zhang, Lei;He, Qiaojun;Yang, Bo;Hu, Yongzhou [Medicinal Chemistry,2013,vol. 9,# 4,p. 581 - 587]

6-METHYLAMINOURACIL Related Search: