ChemicalBook CAS DataBase List Ethyl 2-cyano-3,3-diphenylacrylate

Ethyl 2-cyano-3,3-diphenylacrylate synthesis

3synthesis methods

Product Name:Ethyl 2-cyano-3,3-diphenylacrylate
CAS Number:5232-99-5
Molecular formula:C18H15NO2
Molecular Weight:277.32

The preparation method of Ethyl 2-cyano-3,3-diphenylacrylate includes the following steps: add cyclohexane and benzophenone to the reaction kettle, wait until the benzophenone is completely dissolved, then raise the temperature to 102-104°C and keep it warm. Then, add sodium bicarbonate as a catalyst, add ethyl cyanoacetate into the dripping storage tank, slowly add ethyl cyanoacetate dropwise into the reaction kettle, and react for 16 to 18 hours. During the reaction, the water generated is separated in time, and the reaction is completed. The product Ethyl 2-cyano-3,3-diphenylacrylate is obtained.

119-61-9 Synthesis

119-61-9
759 suppliers
$5.00/10g

105-56-6
432 suppliers
$10.00/5ml

5232-99-5
276 suppliers
$6.00/10g

Yield:5232-99-5 94.1%

Reaction Conditions:

with ammonium acetate;pyrographite in n-heptane for 15 h;Ionic liquid;Reflux;

Steps:

4-7 Example 6 Preparation of ethyl 2-cyano-3,3-diphenylacrylate
According to the scheme in Example 4,Where ammonium acetate feeding scheme,Add 10g for the first time, after 1h of reaction,Then add 1.5g every half hour, the total reaction time is about 15h,The rest is unchanged, and finally the ethyl 2-cyano-3,3-diphenylacrylate is 117.1g,The yield was 94.1%, and the HPLC purity was 99.3%.

References:

Li'anlong Kerun (Zhejiang) New Materials Co., Ltd.;Tianjin Li'anlong New Materials Co., Ltd.;Zheng Hongchao;Zhang Junhua;Li Ying;Jiang Tingting;He Huolei;Sun Chunguang;Li Haiping CN110981752, 2020, A Location in patent:Paragraph 0093-0094; 0099-0104

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1013-88-3 Synthesis

1013-88-3
375 suppliers
$10.00/5g

105-56-6
432 suppliers
$10.00/5ml

5232-99-5
276 suppliers
$6.00/10g

References

119-61-9 Synthesis

119-61-9
759 suppliers
$5.00/10g

631-61-8 Synthesis

631-61-8
757 suppliers
$11.19/100G

64-19-7 Synthesis

64-19-7
1526 suppliers
$10.00/25ML

105-56-6
432 suppliers
$10.00/5ml

71-43-2
670 suppliers
$11.19/25ML

5232-99-5
276 suppliers
$6.00/10g

References

Ethyl 2-cyano-3,3-diphenylacrylate Related Search:

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