ChemicalBook CAS DataBase List N,N'-Dimethylpiperazine

N,N'-Dimethylpiperazine synthesis

15synthesis methods

Product Name:N,N'-Dimethylpiperazine
CAS Number:106-58-1
Molecular formula:C6H14N2
Molecular Weight:114.19

N,N'-Dimethylpiperazine is obtained from piperazine and methanol or formaldehyde under aminating conditions.

110-85-0 Synthesis

110-85-0
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$5.00/5G

50-00-0 Synthesis

50-00-0
843 suppliers
$10.00/25g

106-58-1
232 suppliers
$19.00/25mL

Yield:106-58-1 93%

Reaction Conditions:

with (CuAl)O(x);hydrogen in tetrahydrofuran at 120; under 3750.38 Torr; for 9 h;

Steps:

47

General procedure: The reaction was carried out in the same manner as in Example 10 and 100 mL of a reactor equipped with a magnetic stirrer, using catalyst A 20 mg and the reaction medium was 3 mL of tetrahydrofuran. The reaction was carried out with 1 mmol of the starting material, 1.5 mmol of paraformaldehyde, System air 3 times, and then filled with 0.5MPa H2. And then heated to 120-140 after 9 hours. The reaction temperature, time, and target product are shown in Table 3 below. After the reaction was stopped and cooled to room temperature, the reaction mixture was quantitatively analyzed using an HP 6890/5973 GC-MS gas phase mass spectrometer and an Agilent 7890A (30 m x 0.25 mm x 0.33 [mu] m capillary column, hydrogen flame ion detector) Separation and purification to obtain the target product, the yield of the target product is shown in Table 3-1 and Table 3-2

References:

CN106957232,2017,A Location in patent:Paragraph 0034-0035

110-85-0 Synthesis

110-85-0
549 suppliers
$5.00/5G

67-56-1 Synthesis