API

Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.

Cysteamine indications and liposomal dosage forms

Cysteamine is an orphan drug used in the treatment of cystine deposition disorders to prevent the long-term accumulation of cystine in lysosomes.

Apr 25,2024  API

Fumed Silica: Properties, Synthesis and Uses

Fumed Silica has a wide range of applications in the food, chemical, pharmaceutical, cosmetic and composite industries, where it can be used as an adhesive, antifoam agent, pesticide, thickener, antic

Apr 25,2024  API

2-Chlorobenzaldehyde: Chemical Properties, Pharmacokinetic Characteristics and Toxicity

2-Chlorobenzaldehyde, rapidly excreted in rat urine, undergoes metabolism to 2-chlorohippuric acid and benzyl alcohols, with potential toxicity concerns in CS-related incidents.

Apr 25,2024  API

N-Phenyl-bis(trifluoromethanesulfonimide): Pharmaceutical Synthesis Applications and Green Preparation

N-Phenyl-bis(trifluoromethanesulfonimide) aids in synthesizing antibacterial agents and LRRK2 kinase inhibitors and features an eco-friendly production method.

Apr 25,2024  API

2-Ketoglutaric Acid: Anti-Aging Activities and its Mechanism

2-Ketoglutaric acid enhances stem cell function, regulates gene expression, and shows anti-aging potential across species, suggesting promising applications for longevity.

Apr 25,2024  API

Fmoc-N-Me-Arg(pbf)-OH: Advancing Peptide Chemistry in Biological Applications

Fmoc-N-Me-Arg(pbf)-OH facilitates peptide synthesis, bioorthogonal conjugation, and PET imaging, offering versatile applications in research and therapy.

Apr 25,2024  API

Crystal structure of lithium hydroxide monohydrate

Lithium hydroxide monohydrate, LiOH· H20, the "lithium hydrate" of commerce, was described crystallographically by V. von Lang2 ) as monoclinic prismatic, with the axial ratios a : b : c = 0.8184 : 1

Apr 24,2024  API

Benefits and hazards of cesium chloride on human health

Cesium chloride (CsCl) is an inorganic salt promoted as an alternative cancer therapy and available for purchase as a dietary supplement in the United States.

Apr 24,2024  API

Application of Poly(vinyl alcohol)

Poly(vinyl alcohol) (PVA) is a thermoplastic synthetic polymer (linear polymer) derived from the hydrolysis of poly(vinyl ester) and poly(vinyl ether).

Apr 24,2024  API

Crystal structure of COBALT PHOSPHIDE and its derivatives

The new compound HoCo3P2 was prepared by reaction of the elemental components in a tin flux.

Apr 23,2024  API
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