Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
Pyrroloquinoline quinone disodium salt: Benefits and Safety
Pyrroloquinoline quinone disodium salt (PQQ) is a natural coenzyme in food that has highly efficient antioxidant activity and improves a variety of functions such as mitochondrial activation, growth,
Apr 11,2024 APISalicylaldoxime: Applications in Solvent Extraction and Synthesis Method
Salicylaldoxime, derived from salicylaldehyde and hydroxylamine, is vital in chemistry, medicine, and metallurgy, facilitating metal complexation and extraction processes.
Apr 11,2024 APIExploring APS-5: A Breakthrough in Material Science
APS-5 is a beacon of innovation and potential. This new material is a material for synthesizing advanced polymer structures.
Apr 11,2024 APITetrakis(hydroxymethyl)phosphonium Chloride: Applications as Covalent Cross-Linking Agent and Health Hazards
Tetrakis(hydroxymethyl)phosphonium chloride is a versatile inorganic salt used in various industries for its properties, yet poses health and environmental risks.
Apr 11,2024 APIThe side effects of Omalizumab
Xolair? is a brand of omalizumab. This medication treats allergic asthma, chronic hives, and nasal polyps.
Apr 10,2024 APIAn antineoplastic agent: Epothilone B
Epothilone B is an ideal drug for the treatment of spinal cord injury (SCI), which can reduce scar formation in the lesion site, reactivate the axons' regeneration potential and is convenient for oper
Apr 10,2024 APISeveral mechanisms of action of rituximab
Rituximab has become a mainstay in treating a broad variety of B-cell malignancies.
Apr 10,2024 APIBioassay of 2-(Chloromethyl)Pyridine Hydrochloride for Possible Carcinogenicity
2-(Chloromethyl)pyridine hydrochloride, an aromatic heterocycle used in a variety of syntheses, was selected for bioassay by the National Cancer Institute because of the structural similarity of this
Apr 10,2024 API3-Aminopyridine vs 2-Aminopyridine vs 4-Aminopyridine: Difference between the three
3-Aminopyridine is an important organic intermediate compound used as a plant growth regulator and also in the manufacture of pharmaceuticals, dyes, agrochemicals and oligomers/polymers.
Apr 10,2024 APIUnlocking the Potential of Lactoferrin: Insights into Its Structure, Mechanism, and Multifaceted Applications in Chemistry
The molecular backbone of lactoferrin is characterized by its ability to tightly bind iron ions, a property central to many of its biological functions.
Apr 10,2024 API