Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
Side effects of Arbidol Hydrochloride
Arbidol hydrochloride has the effect of an immunomodulator and also has special antiviral activity against influenza A and influenza B.
Dec 10,2021 APISynthesis and reactions of Isoamyl nitrite
Isoamyl nitrite is a nitrite ester having isopentyl as the alkyl group. It has a role as a vasodilator agent and an antihypertensive agent. It derives from an isoamylol.
Dec 10,2021 APIUses of Carbamazepine
Carbamazepine is a synthetic iminostilbene derivative structurally similar to imipramine, a tricyclic antidepressant. While unrelated structurally, carbamazepine shares a similar therapeutic action wi
Dec 8,2021 APIApplication and Pharmacology of Lorcaserin hydrochloride
Lorcaserin hydrochloride is a hydrochloride obtained by reaction of lorcaserin with one equivalent of hydrochloric acid. Used as an anti-obesity drug. It has a role as a serotonergic agonist and an ap
Dec 7,2021 APIToxicity of 3-Quinuclidinyl benzilate
3-Quinuclidinyl benzilate (QNB) — IUPAC name 1-azabicyclo[2.2.2]octan-3-yl hydroxy(diphenyl)acetate; US Army code EA-2277; NATO code BZ; Soviet code Substance 78— is an odorless and bitter-tasting mil
Dec 3,2021 APIUses of Busulfan
Busulfan was noted to have strong antitumor activity in the 1950s. Because of this, GlaxoSmithKline developed the compound, launching Myleran in 1954 for the treatment of chronic myelogenous leukemia
Nov 30,2021 APIIntroduction of Melanotan I
Melanotan I(Afamelanotide) is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH).
Nov 24,2021 APISide effects of Benzyl benzoate
Benzyl benzoate occurs naturally in Peruvian and Tulu balsams as well as other essential oils. It was used in Vietnam War as a repellant for ticks and mites. Benzyl benzoate was used as an antispasmod
Nov 23,2021 APIUses of benzyl alcohol
As an important synthetic chemical that is also widely produced across nature at modest levels, benzyl alcohol was prepared chemically in small amounts from benzaldehyde and potassium hydroxide via th
Nov 23,2021 APIBischloroethyl nitrosourea —Mechanism of Action
Bischloroethyl nitrosourea (BCNU) is a mustard-gas-derived alkylating agent that underwent clinical trials for use as an antineoplastic agent in the mid-1960s. Intravenous BCNU received US Food and Dr
Nov 18,2021 API