Active Pharmaceutical Ingredients (API), popularly speaking, are the raw materials of medicines, only pharmaceutical raw materials are processed into pharmaceutical preparations , can they become medicines available for clinical use, so drugs we usually eat are the finished drugs through processing. Active Pharmaceutical Ingredients based on its sources can be divided into two major categories ,including chemical synthetic drugs and natural chemical drugs. Chemical synthetic drugs can be divided into organic synthetic drugs and inorganic synthetic drugs. Inorganic synthetic drugs are inorganic compounds ( very few is element), such as aluminum hydroxide, magnesium trisilicate which are used for the treatment of gastric and duodenal ulcers ; organic synthetic drugs are mainly composed of drugs made by basic organic chemical raw materials, through a series of organic chemical reactions (such as aspirin, chloramphenicol, caffeine, etc.). Natural chemical drugs ,based on its sources,can be divided into two categories including biochemical drugs and plant chemical drugs. Antibiotics are generally made by the microbial fermentation, which belongs to the biochemistry category. A variety of semi-synthetic antibiotics occurs in recent years,which are biosynthesis and chemical synthesis combining products.Among active Pharmaceutical Ingredients, the organic synthetic drugs varieties, yields and values have the largest proportion,which are the main pillars of the chemical and pharmaceutical industries. The quality of active Pharmaceutical Ingredients decides whether the formulation is good or bad , so its quality standards are very strict ,countries in the world have developed national pharmacopoeia standards and strict quality control methods for its widely used active Pharmaceutical ingredients.
Unveiling 4-Cyanophenol: A Tale of Chemistry, Applications, and Beyond
This review delves deep into 4-Cyanophenol molecular structure, diverse applications, environmental implications, and the current landscape of research.
Oct 21,2024 APIAluminum Ammonium Sulfate: A Versatile Compound in Chemistry
Aluminum ammonium sulfate, or ammonium alum, is a widely used chemical compound in various industrial and laboratory applications.
Oct 21,2024 APITriphenylmethyl Chloride: A Comprehensive Overview
Triphenylmethyl chloride or trityl chloride (TrCl) is used in the preparation of S-trityl-L-cysteine (STLC), a tight-binding inhibitor of Eg5 that prevents mitotic progression.
Oct 21,2024 APIPreparation and Uses of Citicoline sodium injection
Citicoline sodium injection is an injectable pharmaceutical composition for the treatment of acute craniocerebral trauma and brain surgery-induced disorders of consciousness.
Oct 21,2024 APIEthylmagnesium Bromide: A Versatile Reagent in Organic Synthesis
Ethylmagnesium bromide (EtMgBr) is a crucial organometallic compound widely used in organic synthesis.
Oct 21,2024 APIDL-Serine: History and Therapeutic Potential
DL-Serine, essential for metabolic function and neurological development, requires dietary intake due to insufficient synthesis, with sources including soy, eggs, and fish.
Oct 21,2024 APIRoflumilast: Drug Pharmacology and Clinical Efficacy
Roflumilast is a selective PDE4 inhibitor that inhibits pulmonary and systemic inflammation and rallies symptoms in airway diseases.
Oct 21,2024 APIUnderstanding Sodium Butyrate: Benefits and Mechanisms
Sodium butyrate supports gut health, exhibits anti-tumor activity in colorectal cancer, and enhances beneficial microbiota, emphasizing the importance of a fiber-rich diet.
Oct 21,2024 API2,5-Dibromopyridine: Applications in Organic Chemistry and Green Synthesis
2-amino-5-bromopyridine into a hydrogen bromide solution, reacting for 2-5 hours while controlling the temperature at -5-15 DEG C, thereby obtaining the 2,5-dibromopyridine.
Oct 21,2024 APIAdenosine 5'-Monophosphate: Physiological Role and Applications in Asthma Management
Adenosine 5′-monophosphate is a potent pharmacological agent increasingly used in indirect bronchial challenge tests in patients with asthma. Once inhaled, AMP is rapidly converted to adenosine by the
Oct 21,2024 API