In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders.
Squaric acid analogues in medicinal chemistry
Squaric acid is a symmetrical planar diprotic four-membered oxocarbon compound that possesses unique 2π-pseudo-aromaticity.
Jan 30，2024 Drugs
How is Linzagolix choline synthesised?
The synthesis of Linzagolix choline was carried out by an efficient two-component polymerisation synthesis.
Jan 30，2024 Drugs
How is Belzutifan synthesised?
Belzutifan was prepared by a synthetic route starting from 3,4-dihydrocoumarin, followed sequentially by the synthesis of Indanone Core and Indanone Ketal, and finally concentrating on three consecuti
Jan 29，2024 Drugs
Efficacy and safety of sugammadex sodium in reversing rocuronium-induced neuromuscular blockade in children: An updated
Sugammadex sodium is is more effective and safer in reversing rocuronium-induced neuromuscular blockade in children than traditional antagonistic regimens or placebos.
Jan 26，2024 Drugs
How is Piflufolastat F-18 synthesised?
Piflufolastat F-18 is synthesised from Trimethylammonium Salt and Activated Ester through a series of chemical reactions.
Jan 26，2024 Drugs
Pafolacianine: Synthesis and Introduction
Pafolacianine is an imaging agent. Developed by On Target Laboratories, it has been approved for fluorescence-guided surgery in ovarian cancer.
Jan 25，2024 Drugs
Upacicalcet: Synthesis and Introduction
Upacicalcet is synthesised using aniline as a raw material by chemical reaction.
Jan 24，2024 Drugs
What is the synthetic pathway for Imeglimin hydrochloride?
Imeglimin hydrochloride is synthesised using metformin hydrochloride as a raw material by chemical reaction.
Jan 24，2024 Drugs
Is Relugolix for advanced prostate cancer FDA-approved?
Yes.The US Food and Drug Administration on 18 December 2020 approved the first oral gonadotropin-releasing hormone (GnRH) receptor antagonist, relugolix for adult patients with advanced prostate cance
Jan 23，2024 Drugs
Application and Mechanism of Action of Crotamiton
Crotamiton is an anti-scabies medication,Scabies is a contagious skin disease caused by the microscopic mite Sarcoptes scabiei that causes intense itching.
Jan 23，2024 Drugs