In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders.
Cinacalcet: Application, Mechanism of action and Side effects
Cinacalcet is an orthosteric modulator of the calcium-sensitive receptor (CaSR) and acts as a calcimimetic.
Apr 2，2024 Drugs
6-Mercaptopurine: Mechanism of Action and Mechanism of Resistance
6-Mercaptopurine has been used as an antineoplastic and immunosuppressive agent for decades, but the precise mechanism by which it exerts its cytotoxic effects has not yet been established.
Mar 28，2024 Drugs
The anti-tumour drug Pazopanib: Uses, Mechanism of action and Side effects
Pazopanib is a targeted anticancer drug for the treatment of advanced kidney cancer and advanced soft tissue sarcoma previously treated with chemotherapy.
Mar 28，2024 Drugs
Gefitinib vs Erlotinib vs Afatinib: differences in anticancer drugs
Gefitinib, erlotinib and afatinib are all anticancer drugs widely used in the treatment of advanced non-small cell lung cancer (NSCLC) with proven efficacy.
Mar 28，2024 Drugs
Regorafenib: Uses, Mechanism of Action and Side effects
Regorafenib is a targeted anticancer prescription drug that belongs to the diphenylurea class of multikinase inhibitors, targeting angiogenic receptors (VEGFR1-3, TIE2), stromal receptors (PDGFR-β, FG
Mar 27，2024 Drugs
Antitumour drug Lenalidomide: Indications and Side Effects
Lenalidomide is a targeted immunomodulatory drug with multiple mechanisms of action. It has anti-tumour, anti-angiogenic and anti-inflammatory properties.
Mar 26，2024 Drugs
Febuxostat: Application, Mechanism of Action and Side Effects
Febuxostat is a medication used to manage and treat hyperuricaemia and gout. It is also a xanthine oxidase inhibitor.
Mar 26，2024 Drugs
5-Azacytidine: Mechanism of Action AND Mechanism of Resistance
5-Azacytidine (NSC-102816), 4-amino-1-β-d-ribofuranosyl-1,3,5-triazine- 2(1H)-one, 5-azacitidine, C8H12N4O5, Mr 244.21, is a pyrimidine analog that was first isolated as a fermentation product from St
Mar 16，2024 Drugs
Methotrexate: Mechanism of Action and Mechanisms of Resistance
Methotrexate can inhibit dihydrofolate reductase (DHFR, Ki = 10?11 M), a key enzyme for the maintenance of biologically active intracellular reduced folate pools.
Mar 16，2024 Drugs
Flurbiprofen: Synthesis and Application
Flurbiprofen has been used at 150 ~ 300 mg/d in the treatment of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Mar 16，2024 Drugs