In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders.
How Abemaciclib works in treating breast cancer
Preclinical studies have shown that continuous inhibition of CDK4/6 by abemaciclib inhibits phosphorylation of the retinoblastoma protein, which becomes inactivated.
Nov 10，2023 Drugs
What is the clinical efficacy of Baloxavir marboxil
A single oral dose of baloxavir marboxil in tablet form improves medication adherence and rapidly reduces viral titres in paediatric influenza patients
Nov 10，2023 Drugs
Vonoprazan FuMarate for the treatment of gastric ulcer and Helicobacter pylori infection disease
Vonoprazan fumarate, a potassium-competitive acid blocker(P-CAB), produces a stronger acid-inhibitory effect than proton pump inhibitors (PPIs).
Nov 10，2023 Drugs
Use of the anti-HIV drug (Dolutegravir sodium)
Dolutegravir sodium is an oral, World Health Organisation-recommended first-line antiretroviral drug that belongs to a class of drugs called HIV integrase inhibitors.
Nov 10，2023 Drugs
Therapeutic potential and mechanism of action of Crisaborole
Crisaborole is a non-steroidal topical medication for the treatment of mild-moderate atopic dermatitis.
Nov 9，2023 Drugs
Can Canagliflozin heMihydrate treat Glioblastoma(GBM) patients?
Canaglifozin inhibits glioblastoma in vitro and the mechanism of action is related to the activation of AMPK.
Nov 9，2023 Drugs
Can Capmatinib treat non-small cell lung cancer (NSCLC) in adults ?
Capmatinib is an FDA-approved targeted drug for the treatment of adult patients with non-small cell lung cancer(NSCLC).
Nov 8，2023 Drugs
What cancers can Dabrafenib Mesylate treat?
Dabrafenib mesylate in combination with trametinib dimethyl sulfoxide is used to treat cancer patients with a certain BRAF gene mutation, such as: Treating undifferentiated thyroid cancer that is loca
Nov 7，2023 Drugs
Adverse reactions of Crizotinib in the treatment of Inflammatory myofibroblastic tumour (IMT)
The most common adverse reactions (≥35%) in pediatric patients were vomiting, nausea, diarrhea, abdominal pain, rash, vision disorder, upper respiratory tract infection, cough, pyrexia, musculoskeleta
Nov 3，2023 Drugs
How is Tesamorelin administered?
Tesamorelin is a powder medication that must be mixed with a liquid (diluent) before use. It is injected under the skin and usually given once a day.
Oct 19，2023 Drugs