In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders.
Fulvestrant: a major breakthrough in breast cancer treatment
Fulvestrant, an anti-estrogenic breast cancer treatment, was approved by the US FDA in September 2002 and approved by the European Union in April 2004 for marketing in Europe.
Aug 31，2023 Drugs
Anastrozole: Applications, pharmacology and side effects
Anastrozole, a third-generation nonsteroidal aromatase inhibitor, is effective in postmenopausal women with estrogen receptor-positive metastatic breast cancer.
Jul 18，2023 Drugs
Regorafenib: Applications, metabolism, pharmacokinetics and toxicity
Regorafenib is a new oral small molecule multi-kinases inhibitor. It can inhibit the target kinases associated with angiogenesis and tumorigenesis.
Jul 17，2023 Drugs
Acyclovir: Applications and side effects
Acyclovir is an antiviral drug. However, it is not a cure for these infections. The viruses that cause these infections continue to live in the body even between outbreaks.
Jun 27，2023 Drugs
Idebenone: Applications and pharmacology
Idebenone is used for Alzheimer's disease, Huntington’s disease, liver disease, and heart disease. It is also used for a number of inherited disorders including a condition that causes vision loss.
Jun 25，2023 Drugs
Prilocaine: Applications and dosage
Prilocaine is an amino acid amide in which N-propyl-DL-alanine and 2-methylaniline have combined to form the amide bond; used as a local anaesthetic.
Jun 19，2023 Drugs
Baricitinib: Pharmacodynamics and pharmacokinetics
Baricitinib is a selective and reversible Janus kinase 1 (JAK1) and 2 (JAK2) inhibitor. Janus kinases belong to the tyrosine protein kinase family.
Jun 7，2023 Drugs
Levamisole hydrochloride: Applications, metabolism and side effects
Levamisole hydrochloride has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic receptor.
May 30，2023 Drugs
Lorlatinib (PF-06463922): Pharmacodynamics, pharmacokinetics and adverse events
Lorlatinib is a small molecule inhibitor of ALK and ROS1 kinase developed by Pfizer for the treatment of ALK-positive non-small cell lung cancer. It has a role as an antineoplastic agent.
May 19，2023 Drugs
Benzoyl peroxide: Medical use, mechanism and side effects
Benzoyl Peroxide is a peroxide with antibacterial, irritant, keratolytic, comedolytic, and anti-inflammatory activity.
May 16，2023 Drugs