Ginkgolide B: Origin, Pharmacokinetics and Neuroprotective Effects
Ginkgolide B from Ginkgo biloba offers neuroprotection by reducing infarct size, enhancing survival, and modulating cellular pathways in ischemic strokes.
Nov 11，2024 Natural Products
3-Butenenitrile: Occurrence, Metabolism and Health Effects
3-Butenenitrile plays a key role in industry and surgery, with potential health impacts. Subtoxic exposure may enhance enzyme activities, offering protective effects.
Nov 11，2024 API
Nicotinic Acid: Mechanism of Action, Effect on Lipid Profile and Cardiovascular Risk
Nicotinic acid improves lipid profiles via GPR109A activation, apoB degradation, and CETP activity modulation, yet its efficacy combined with statins warrants further investigation.
Nov 11，2024 API
Phosphorus oxychloride:Reactions with water,Uses,Hazards and Warnings
Phosphorus oxychloride is a colourless liquid with the formula POCl3.
Nov 11，2024 Organic reagents
Why is febuxostat better than allopurinol?
The cardiovascular safety of febuxostat compared to allopurinol for treating gout remains equivocal. Febuxostat had a better safety outcome compared with allopurinol.
Nov 11，2024 API
Linagliptin: A Potent DPP-4 Inhibitor for Effective Management of Type 2 Diabetes Mellitus
Linagliptin is a potent, selective dipeptidyl peptidase-4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus (T2DM).
Nov 11，2024 API
Osthole: A Promising Natural Coumarin Derivative with Diverse Therapeutic Applications
Osthole, has garnered significant attention in recent years due to its wide range of biological activities and potential therapeutic applications.
Nov 11，2024 API
Lurasidone Hydrochloride: Pharmacodynamics, Clinical Effectiveness and Adverse Effects
Lurasidone hydrochloride is clinically beneficial in treating patients with schizophrenia and bipolar depression.
Nov 8，2024 API
Prucalopride Succinate: Pharmacodynamics, Pharmacokinetic Properties and Adverse Effects
Prucalopride Succinate is a serotonin-4 (5-HT4) receptor agonist indicated for the treatment of chronic idiopathic constipation (CIC) in adults.
Nov 8，2024 Biochemical Engineering
Diverse Properties of Rosmarinic Acid: From Herbal Material to Therapeutic Administration Routes
Rosmarinic acid (RA) is a compound found in various plants.RA was clinically investigated in atopical dermatitis due to its in vitro and in vivo anti-inflammatory effects.
Nov 8，2024 API