Cisplatin: Clinical Applications in Cancer Treatment and its Toxicity
Cisplatin is crucial in cancer treatment but faces challenges due to nephrotoxicity, ototoxicity, and gastrointestinal issues, prompting research into improving efficacy and reducing side effects.
Sep 3，2024 API
The synthesis method of 1-BOC-Piperazine
N-Boc piperazine (1-BOC-Piperazine) belongs to the monosubstituted piperazine compounds.
Sep 2，2024 Organic reagents
Atorvastatin calcium: Chemical property, Spectroscopy, and Side effects
Atorvastatin calcium (LIPITOR ) is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3- methylglutaryl-coenzyme A to mevalonate, a precursor of
Sep 2，2024 Drugs
Simvastatin: uses and side effects
Simvastatin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglyceride
Sep 2，2024 Drugs
Afatinib dimaleate: Chemical properties, Indications, Mechanism of action and Side effects
Afatinib dimaleate is very soluble in water and aqueous buffers with a pH of 1 to 6 (> 50 mg/ mL). The free base is strongly lipophilic (log P = 4.7) but is strongly pH dependent.
Sep 2，2024 Drugs
N,N-Dimethylethylenediamine: A Key Chemical Compound in Modern Applications
N, N-Dimethylethylenediamine is an organic compound that has gained prominence in various fields of chemistry and industry.
Sep 2，2024 API
P-Toluenesulfonamide: A Versatile Compound in the Chemical Industry
P-Toluenesulfonamide (p-TSA) is a vital chemical compound widely used across various industries, particularly in the chemical and pharmaceutical sectors.
Sep 2，2024 API
Vonoprazan Fumarate: Physicochemical Properties and Pharmacokinetics
Vonoprazan fumarate, a potent potassium-competitive acid blocker with high pKa, exhibits rapid absorption, extensive CYP metabolism, and minimal renal excretion.
Sep 2，2024 API
MOPS: Versatile Applications and its Production Method
MOPS is a buffering agent used in biotechnology, produced via synthesis from 1,3-bromo-chloropropane and morpholine, purified for stability in scientific applications.
Sep 2，2024 API
Nonapeptide-1: Applications in Skin Care and its Preparation Method
Nonapeptide-1, a synthetic peptide that inhibits alpha-melanocyte-stimulating hormone, effectively lightens sunspots and is efficiently produced with the Wir Gp071 variant for commercial use.
Sep 2，2024 API