How is Anamorelin Monohydrochloride synthesised?
Anamorelin Monohydrochloride was synthesised starting from 2,2- Dimethylhydrazine by polymerisation of intermediate compounds.
Jan 18，2024 Drugs
Idebenone: A Multifaceted Compound for Antioxidant Activity and Mitochondrial Function
Idebenone acts as an electron carrier and enhances antioxidant defense mechanisms, protecting against mitochondrial dysfunction through multiple pathways. NQO1 activation is crucial for its activity.
Jan 18，2024 API
Glucose oxidase: a versatile enzyme with applications in food, textile, and biofuel industries
Glucose oxidase is a versatile enzyme used in food, textile, and biofuel industries, offering benefits like improved product quality, cost-effectiveness, and lower environmental impact.
Jan 18，2024 API
Avacopan: Synthesis and Introduction
Avacopan is synthesised using ethyl 3-(4-nitrophenyl)-3-oxo-propanoate as a raw material by chemical reaction.
Jan 18，2024 Drugs
An antibody drug conjugate: Enfortumab Vedotin
Enfortumab vedotin (EV) is an antibody?drug conjugate (ADC) consisting of a fully humanized monoclonal antibody targeting nectin-4 linked to the microtubule-disrupting agent monomethyl auristatin E (
Jan 17，2024 API
The introduction of Darolutamide (ODM-201)
Darolutamide (ODM-201) is a structurally distinct non-steroidal androgen receptor (AR) antagonist being developed by Orion and Bayer as a treatment for prostate cancer.
Jan 17，2024 API
An orally PI3K inhibitor: Alpelisib
Alpelisib -an orally available phosphatidylinositol 3-kinase (PI3K) inhibitor with specific activity against PI3K alpha (PI3Kα)-is being developed by Novartis for the treatment of breast cancer.
Jan 17，2024 API
Safety and Efficacy of Chloral Hydrate in Outpatient Pediatrics for Sedation
Chloral hydrate is a clinical sedative drug used for the short-term treatment of insomnia and to relieve anxiety and induce sleep prior to surgery.
Jan 17，2024 Drugs
Is 1,3-Propane sultone carcinogenic to humans?
1,3-Propane sultone (1,3-PS) is a directly alkylating, genotoxic and carcinogenic substance.
Jan 17，2024 API
Streptomycin Sulfate: Biological Activities, Efficacy in Humans and Safety
Streptomycin sulfate is an aminoglycoside antibiotic used to treat Gram-negative infections, including tuberculosis. It has potential safety concerns and is no longer a first-line option.
Jan 17，2024 API