Mechanism of action of Nikkomycin Z
Nikkomycin Z is an experimental compound with antifungal properties. Like all nikkomycins, it consists of a pyrimidine nucleoside linked to a short peptide moiety. There are more than 14 naturally occ
Mar 31，2022 API
Mechanism and Toxicity of Haloprogin
Haloprogin (3-iodo-2-propynyl 2,4,5-trichlorophenyl ether; Halotex cream) has been used as a topical agent for the treatment of dermatophyte infections. Haloprogin was synthesized in 1963 by Seki as o
Mar 31，2022 API
Mechanism of action of Griseofulvin
Griseofulvin (MW 352.5 daltons) is a metabolite of Penicillium griseofulvum and P. janczewskii that disrupts the fungal mitotic spindle and inhibits cell wall synthesis. The structure is shown below.
Mar 31，2022 API
Mechanism and Side-effects of Flucytosine
Flucytosine (Ancotil, Ancobon) is a fluorinated pyrimidine analog that is primarily used in combination with amphotericin B or fluconazole for the treatment of invasive yeast infections. Rapid emergen
Mar 31，2022 API
Mechanism and Pharmacodynamics of Rilopirox
Rilopirox, 6-[[p-(p-chlorophenoxy)phenoxy]methyl]-1-hydroxy-4- methyl-2(1H)-pyridone, is a new water insoluble fungicidal antimycotic. It is the second antifungal agent of the hydroxypyridone antifung
Mar 31，2022 API
Mechanism and Side effects of Ciclopirox
Ciclopirox is a synthetic hydroxypyridone, and ciclopirox olamine is the ethanolamine salt of ciclopirox. Its chemical name is the 2-aminoethanol salt of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone
Mar 31，2022 API
Mechanism of action of Amorolfine
Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the US
Mar 31，2022 API
Application of Etomidate
Etomidate is a non-barbiturate intravenous sedative drug, which is a hydroxylated salt of imidazole.
Mar 31，2022 API
Performance and use of Isothiazolinone
Isothiazolinone is a fungicide with the chemical formula C8H9ClN2O2S2
Mar 31，2022 API
The role of N-fluorobisbenzenesulfonamide in chemical synthesis
N-Fluorobenzenesulfonimide (NFSI) is a colorless crystalline powder with a melting point of 114–116 °C
Mar 31，2022 API