Phloroglucinol compounds of natural origin
Phloroglucinol is a benzenetriol with hydroxy groups at position 1, 3 and 5. It has a role as an algal metabolite. Phloroglucinol is a natural product found in Artemisia dolosa, Koenigia coriaria, and
Mar 31，2022 Drugs
Application and Pharmacology of 2-phenylethanaminium
Phenethylamine is a natural product found in Vitis vinifera, Trypanosoma brucei, and other organisms with data available. 2-phenylethylamine is a phenylethylamine having the phenyl substituent at the
Mar 31，2022 Drugs
The synthesis of methyl orange
Methyl orange is an organic substance with the chemical formula of C14H14N3SO3Na, which is often used as an acid-base indicator.
Mar 31，2022 API
Mechanism of action of Nikkomycin Z
Nikkomycin Z is an experimental compound with antifungal properties. Like all nikkomycins, it consists of a pyrimidine nucleoside linked to a short peptide moiety. There are more than 14 naturally occ
Mar 31，2022 API
Mechanism and Toxicity of Haloprogin
Haloprogin (3-iodo-2-propynyl 2,4,5-trichlorophenyl ether; Halotex cream) has been used as a topical agent for the treatment of dermatophyte infections. Haloprogin was synthesized in 1963 by Seki as o
Mar 31，2022 API
Mechanism of action of Griseofulvin
Griseofulvin (MW 352.5 daltons) is a metabolite of Penicillium griseofulvum and P. janczewskii that disrupts the fungal mitotic spindle and inhibits cell wall synthesis. The structure is shown below.
Mar 31，2022 API
Mechanism and Side-effects of Flucytosine
Flucytosine (Ancotil, Ancobon) is a fluorinated pyrimidine analog that is primarily used in combination with amphotericin B or fluconazole for the treatment of invasive yeast infections. Rapid emergen
Mar 31，2022 API
Mechanism and Pharmacodynamics of Rilopirox
Rilopirox, 6-[[p-(p-chlorophenoxy)phenoxy]methyl]-1-hydroxy-4- methyl-2(1H)-pyridone, is a new water insoluble fungicidal antimycotic. It is the second antifungal agent of the hydroxypyridone antifung
Mar 31，2022 API
Mechanism and Side effects of Ciclopirox
Ciclopirox is a synthetic hydroxypyridone, and ciclopirox olamine is the ethanolamine salt of ciclopirox. Its chemical name is the 2-aminoethanol salt of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone
Mar 31，2022 API
Mechanism of action of Amorolfine
Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the US
Mar 31，2022 API