Mechanism of action of Griseofulvin
Griseofulvin (MW 352.5 daltons) is a metabolite of Penicillium griseofulvum and P. janczewskii that disrupts the fungal mitotic spindle and inhibits cell wall synthesis. The structure is shown below.
Mar 31,2022 APIMechanism and Side-effects of Flucytosine
Flucytosine (Ancotil, Ancobon) is a fluorinated pyrimidine analog that is primarily used in combination with amphotericin B or fluconazole for the treatment of invasive yeast infections. Rapid emergen
Mar 31,2022 APIMechanism and Pharmacodynamics of Rilopirox
Rilopirox, 6-[[p-(p-chlorophenoxy)phenoxy]methyl]-1-hydroxy-4- methyl-2(1H)-pyridone, is a new water insoluble fungicidal antimycotic. It is the second antifungal agent of the hydroxypyridone antifung
Mar 31,2022 APIMechanism and Side effects of Ciclopirox
Ciclopirox is a synthetic hydroxypyridone, and ciclopirox olamine is the ethanolamine salt of ciclopirox. Its chemical name is the 2-aminoethanol salt of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone
Mar 31,2022 APIMechanism of action of Amorolfine
Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the US
Mar 31,2022 APIApplication of Etomidate
Etomidate is a non-barbiturate intravenous sedative drug, which is a hydroxylated salt of imidazole.
Mar 31,2022 APIPerformance and use of Isothiazolinone
Isothiazolinone is a fungicide with the chemical formula C8H9ClN2O2S2
Mar 31,2022 APIThe role of N-fluorobisbenzenesulfonamide in chemical synthesis
N-Fluorobenzenesulfonimide (NFSI) is a colorless crystalline powder with a melting point of 114–116 °C
Mar 31,2022 APIThe preparation method of p-nitrobenzoic acid
P-Nitrobenzoic acid is an intermediate in organic synthesis of medicines, dyes, veterinary drugs, and photosensitive materials.
Mar 31,2022 APIThe role of diethylene glycol dimethy in chemical production
Diethylene glycol dimethyl ether (DMDE for short) is a colorless neutral liquid with ether odor, boiling point 162 ℃,
Mar 31,2022 API












