Mechanism of action of Griseofulvin

Griseofulvin (MW 352.5 daltons) is a metabolite of Penicillium griseofulvum and P. janczewskii that disrupts the fungal mitotic spindle and inhibits cell wall synthesis. The structure is shown below.

Mar 31,2022  API

Mechanism and Side-effects of Flucytosine

Flucytosine (Ancotil, Ancobon) is a fluorinated pyrimidine analog that is primarily used in combination with amphotericin B or fluconazole for the treatment of invasive yeast infections. Rapid emergen

Mar 31,2022  API

Mechanism and Pharmacodynamics of Rilopirox

Rilopirox, 6-[[p-(p-chlorophenoxy)phenoxy]methyl]-1-hydroxy-4- methyl-2(1H)-pyridone, is a new water insoluble fungicidal antimycotic. It is the second antifungal agent of the hydroxypyridone antifung

Mar 31,2022  API

Mechanism and Side effects of Ciclopirox

Ciclopirox is a synthetic hydroxypyridone, and ciclopirox olamine is the ethanolamine salt of ciclopirox. Its chemical name is the 2-aminoethanol salt of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone

Mar 31,2022  API

Mechanism of action of Amorolfine

Amorolfine is available for topical use in 0.25% cream and 5% nail lacquer formulation for the treatment of onychomycosis in European countries and Japan. However, amorolfine is not approved in the US

Mar 31,2022  API

Application of Etomidate

Etomidate is a non-barbiturate intravenous sedative drug, which is a hydroxylated salt of imidazole.

Mar 31,2022  API

Performance and use of Isothiazolinone

Isothiazolinone is a fungicide with the chemical formula C8H9ClN2O2S2

Mar 31,2022  API

The role of N-fluorobisbenzenesulfonamide in chemical synthesis

N-Fluorobenzenesulfonimide (NFSI) is a colorless crystalline powder with a melting point of 114–116 °C

Mar 31,2022  API

The preparation method of p-nitrobenzoic acid

P-Nitrobenzoic acid is an intermediate in organic synthesis of medicines, dyes, veterinary drugs, and photosensitive materials.

Mar 31,2022  API

The role of diethylene glycol dimethy in chemical production

Diethylene glycol dimethyl ether (DMDE for short) is a colorless neutral liquid with ether odor, boiling point 162 ℃,

Mar 31,2022  API
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