PHYSICAL PROPERTIES OF LITHIUM METAL
Davy and Brande independently prepared lithium metal in 1818 by the electrolysis of lithium oxide. However, larger quantities of the metal were prepared by Bunsen and Mattiessen in 1855 by electrolysi
Dec 16，2019 Inorganic chemistry
Sulforaphene – Pharmacological action and its Application in Cancer Treatment
Sulforaphene, or raphanin, is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. It was first described by G. Ivanovics and S. Horvath i
Dec 16，2019 Plant extracts
What is Chelidonine, and what can it be used for?
Chelidonine, also named ranunculine, is a benzophenanthridine alkaloid isolated from the whole plant of Chelidonium majus. L. It has been used as a painkiller in clinical treatment based on its morphi
Dec 16，2019 Antipyretic analgesics
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide - reaction / application on synthetic works
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide is an organic photoinitiator. It is also an important organic intermediate to synthetize polymerization initiators in the area of materials science, mis
Dec 13，2019 Organic reagents
N-phenylpiperidin-4-amine dihydrochloride- reaction / application on synthetic works
N-phenylpiperidin-4-amine dihydrochloride is an important organic intermediate to synthetize substituted phenylpiperidin products.
Dec 13，2019 Organic Chemistry
Dabrafenib Mesylate(GSK-2118436B)- Pharmacodynamics & Bioactivity
Dabrafenib Mesylate is a salt form of Dabrafenib. Dabrafenib is an inhibitor of certain mutated forms of BRAF kinase, several of which may be associated with stimulating tumour growth.
Dec 13，2019 Inhibitors
Cabozantinib (XL184)- antitumour effects
Cabozantinib is a small molecule inhibitor of multiple tyrosine kinase receptors. In vitro, it has demonstrated inhibitory activity against RET, MET and VEGFR-2 and against the RET mutant M918T.
Dec 13，2019 Antineoplastic agents
MDV-3100 (Enzalutamide)- Pharmacodynamic Properties
MDV3100, known as Enzalutamide, is a second-generation androgen receptor (AR) signaling inhibitor. It is able to inhibit binding of androgens to the AR, AR nuclear translocation, and the association o
Dec 13，2019 Inhibitors
Dabigatran etexilate (BIBR-1048)- Pharmacology
Dabigatran etexilate (Pradaxa, BIBR 1048, Boehringer Ingelheim) is the prodrug of dabigatran (originally known as BIBR 953), a potent, nonpeptidic small molecule.
Dec 13，2019 Inhibitors
Larotrectinib (LOXO-101)- Pharmacodynamics
Larotrectinib (VITRAKVIR) is an orally administered, small molecule, highly-selective, tropomyosin receptor kinase (TRK) inhibitor that was developed by Loxo Oncology in collaboration with Bayer AG.
Dec 13，2019 Inhibitors