Uses of α-pinene

α-pinene extracted from Pinheiro Mde A and other oils was used in the treatment of gastric ulcer in mice and it has been found that α-pinene has significant anti-ulcer activity.

Oct 12,2019  Plant extracts

Nickelocene: Chemical Properties and Uses

Nickelocene, also known as dicyclopentadienyl nickel, is a dark green crystal. Due to the filling electrons in the anti-bond orbital of the molecular orbital, the structure is unstable.

Oct 12,2019  Organometallic compounds

Flumetralin: Chemical properties, Uses, and Toxicity

Flumetralin is a contact and local systemic tobacco side bud inhibitor with high-efficiency. It is used for flue-cured tobacco, sun-cured tobacco and cigar.

Oct 12,2019  Chemical pesticides ​

Buspirone: Pharmacokinetics,side effects and mechanism of action

Buspirone, also known as Buspa, and Hisblon, is a new generation of non-BZ anxiolytic drug with anti-anxiety effects and a different mechanism of action from that of benzodiazepines.

Oct 12,2019  Chemical pesticides ​

Toxicity and Uses of Iprobenfos

Iprobenfos is a systemic organophosphorus fungicide, and mainly used in the control of rice blast with a stronger efficacy and longer duration than that of Kitazin.

Oct 12,2019  Chemical pesticides ​

Biological activity of Inhibitor AC220

Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively.

Oct 11,2019  Inhibitors

Biological activity of PLX-4720

PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations).

Oct 11,2019  Inhibitors

CP-690550 as an Inhibitor

Tofacitinib citrate is a king of drugs developed by the US pharmaceutical company Pfizer for treating rheumatoid arthritis, trade name Xeljanz.

Oct 11,2019  Inhibitors

Biological activity of GSK1120212

Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2.

Oct 11,2019  Inhibitors

Biological activity ABT-888

Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays.

Oct 11,2019  Inhibitors
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