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Natural Products

Organic compounds isolated and extracted from the body of naturally existing organisms are collectively known as natural products. They are formed through photosynthesis and biochemical reaction inside the bodies of animals and plants. For example, starch comes from the seeds, stems and roots block of plants; meat, dairy products, eggs and cereals, beans are the basic source of protein; many drugs such as ephedrine, menthol and gall bladder are extracted from the corresponding organisms; indigo blue dye, red dye alizarin are respectively extracted from natural indigo leafs and madder; natural spices musk, jasmine, and rose also originate from the corresponding animal and plant body. The Chengdu Institute of Biology (Chinese academy of sciences) had promoted the research aspects of the natural products from the early 1960s, starting large-scale resources investigation of plants, amphibians, reptiles and microorganisms, mastering a lot of biological resources information in the southwest and the surrounding area. In the research aspect of active ingredients of natural medicinal plant, people have carried out research on the chemical constituents of hundreds of medicinal plants, isolating and identifying of a number of natural chemical components such as saponins, terpenoids, alkaloids, and flavonoids. Through this, people have further found over 100 kinds of novel natural compounds of some new structural skeleton and successfully developed a new herbal drug “DAXXK” for the treatment of cardiovascular disease. It has achieved good sales around the country with a total output value of 2.7 billion yuan and profits of 1.1 billion.

What is Digitoxin?

Digitoxin is a cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting .

Jan 24,2022  Natural Products

Betulin: Properties, Application, pharmacokinetics, Synthesis etc.

Betulin was first observed by Lowitz in 1788, from the sublimation products of birch bark. Betulinic acid (3β, hydroxyl-lup-20(29)-en-28-oic acid) (BA) is a triterpenoid of lupane-structured pentacycl

Oct 15,2021  Natural Products

What is apigenin?

Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities.

Feb 26,2020  Natural Products

Biological activity of Salidroside

Salidroside is a natural antioxidant extracted from medicinal food plant?Rhodiola rosea and it is a prolyl endopeptidase inhibitor, which has cardioprotective, antidiabetic, antidepressant, anxiolytic

Feb 21,2020  Natural Products

What is 7,9-ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione?

7,9-Ditert-butyl-1-oxaspiro[4.5]deca-6,9-diene-2,8-dione (C17H24O3, CAS registry No. 82304-66-3) is an oxaspiro compound that is 1-oxaspiro[4.5]deca-6,9-diene-2,8-dione carrying two additional tert-bu

Feb 13,2020  Natural Products

What is theaflavin-3-gallate?

Theaflavin-3-gallate, a black tea theaflavin monomer, formed in the oxidation of epicatechin (EC) and epigallocatechin gallate (EGCG) at the ratio of 1:1, is regarded as the biologically important act

Feb 13,2020  Natural Products

What is Isoescin IB?

Escin (aescin) is a mixture of triterpene saponins and constitutes the major active ingredient in horse chestnut (Aesculus hippocastanum) seed extracts. Escin exhibits remarkable anti-inflammatory, an

Feb 13,2020  Natural Products

What is Euphporbia factor L3?

Euphorbia factor L3 (EFL3, chemically named 5,15-Diacetyl-3-benzoyllathyrol) was obtained as colorless crystal from dichloromethane-petroleum ether. The molecular weight was determined by EIMS showing

Feb 13,2020  Natural Products

What is Escin IA?

Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity.

Feb 13,2020  Natural Products

What is Kaempferol?

Kaempferol (3,5,7‐trihydroxy‐2‐[4‐hydroxyphenyl]‐4H‐1‐benzopyran‐4‐one) is a yellow bioactive flavonoid, which is present inmany edible plants such as tea, cabbage, broccoli, endive, kale, beans, toma

Feb 12,2020  Natural Products
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