| Identification | More | [Name]
Phenyl chlorothionocarbonate | [CAS]
1005-56-7 | [Synonyms]
CHLOROTHIOFORMIC ACID O-PHENYL ESTER
CHLOROTHIOFORMIC ACID PHENYL ESTER
O-PHENYL CHLOROTHIOCARBONATE
O-PHENYL CHLOROTHIOFORMATE
O-PHENYL CHLOROTHIONOFORMATE
PHENYL CHLOROTHIONOCARBONATE
PHENYL CHLOROTHIONOFORMATE
PHENYL CHLOROTHIOXOFORMATE
PHENYL THIONOCHLOROFORMATE
Carbonochloridothioicacid,O-phenylester
phenyl thioxochloroformate
HENYL CHLOROTHIONOCARBONATE
Phenylchlorothionocarbonate~Phenylthionochloroformate
Phenyl thiochloroformate.
Phenoxythiocarbonyl chloride
Phenyl chlorothionoformate, 98+%
Formic acid, chlorothio-, O-phenyl ester
O-Phenyl carbonochloridothioate
(Phenoxy)thioformyl chloride
Chloridothiocarbonic acid O-phenyl ester | [EINECS(EC#)]
213-736-4 | [Molecular Formula]
C7H5ClOS | [MDL Number]
MFCD00004920 | [Molecular Weight]
172.63 | [MOL File]
1005-56-7.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR YELLOW LIQUID | [Melting point ]
51 °C | [Boiling point ]
81-83 °C/6 mmHg (lit.) | [density ]
1.248 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.581(lit.)
| [Fp ]
179 °F
| [storage temp. ]
0-6°C | [solubility ]
Chloroform, Ethyl Acetate | [form ]
Liquid | [color ]
Clear yellow | [Specific Gravity]
1.248 | [Water Solubility ]
decomposes | [Sensitive ]
Moisture Sensitive | [BRN ]
774830 | [InChI]
InChI=1S/C7H5ClOS/c8-7(10)9-6-4-2-1-3-5-6/h1-5H | [InChIKey]
KOSYAAIZOGNATQ-UHFFFAOYSA-N | [SMILES]
C(Cl)(=S)OC1=CC=CC=C1 | [CAS DataBase Reference]
1005-56-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
3
| [F ]
10-21 | [REACH Registrations]
Active | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29309070 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
CLEAR YELLOW LIQUID | [Uses]
Phenyl Chlorothionoformate is used in the preparation of an bicyclic thymidine analogs as selective inhibitors of Thymidine monophosphate kinase Mycobacterium tuberculosis (TMPKmt).
| [Purification Methods]
Purify it by dissolving in CHCl3, washing with H2O, drying (CaCl2), filtering, evaporating and distilling twice under a vacuum to give a clear yellow liquid. It is reactive and POISONOUS—work in a fume cupboard. Store it in sealed ampoules under N2. A possible impurity is O,O'-diphenyl thiocarbonate which has m 106o and remains behind in the distilling flask. [B.gemann et al. in Methoden Der Organischen Chemie (Houben-Weyl) 4th edn (E. Müller Ed.) Vol 9 Schwefel-Selen-Tellur Verbindungen pp. 807-808 1955, Rivier & Schalch Helv Chim Acta 6 612 1923, Kalson Chem Ber 20, 2384 1987, Rivier & Richard Helv Chim Acta 8 490 1925, Sch.nberg & Varga Justus Liebigs Ann Chem 483 176 1930, Sch.nberg & Vargha Chem Ber 64 1390 1931, Beilstein 6 III 609.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|