| Identification | Back Directory | [Name]
5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5- | [CAS]
1006335-39-2 | [Synonyms]
ISPA-28
ISPA 28,ISPA28
ISPA-28 >=98% (HPLC)
5-IsoxazolecarboxaMide, N-(2,3-dihydro-1,5-
N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-5-Isoxazolecarboxamide | [Molecular Formula]
C21H24N6O3 | [MDL Number]
MFCD08106635 | [MOL File]
1006335-39-2.mol | [Molecular Weight]
408.454 |
| Chemical Properties | Back Directory | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble5mg/mL, clear (warmed) | [form ]
powder | [pka]
10.98±0.20(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3[1][2]. | [IC 50]
Plasmodium | [storage]
Store at -20°C | [References]
[1] Sanjay A Desai, et al. Ion and Nutrient Uptake by Malaria Parasite-Infected Erythrocytes. DOI:10.1111/j.1462-5822.2012.01790.x
[2] Wang Nguitragool, et al. Proteolysis at a Specific Extracellular Residue Implicates Integral Membrane CLAG3 in Malaria Parasite Nutrient Channels. |
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