| Identification | Back Directory | [Name]
6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, potassium salt (1:1), (3S,5R,6E)- | [CAS]
1009811-63-5 | [Synonyms]
Fluvastatin potassium
6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, potassium salt (1:1), (3S,5R,6E)- | [Molecular Formula]
C24H26FNO4.K | [Molecular Weight]
450.57 |
| Hazard Information | Back Directory | [Uses]
(3S,5R)-Fluvastatin (potassium) is a synthetic hypolipidemic drug that inhibits HMG-CoA reductase activity. (3S,5R)-Fluvastatin (potassium) has similar antioxidative effects on copper ion-induced LDL oxidation compared to its 3R,5S enantiomer. (3S,5R)-Fluvastatin (potassium) and its metabolites demonstrate a potential to exhibit anti-atherosclerotic effects through their antioxidative activities. (3S,5R)-Fluvastatin (potassium) is clinically utilized as part of a racemic mixture for reducing plasma cholesterol levels. | [References]
[1] In vitro inhibitory effects of the optical isomers and metabolites of fluvastatin on copper ion-induced LDL oxidation DOI:10.1248/bpb.22.971 |
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