| Identification | Back Directory | [Name]
Ethanone, 1-[4-(4-chloro-3-methoxyphenyl)-1-piperazinyl]-2-[3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]- | [CAS]
1010073-75-2 | [Synonyms]
CCX354
CCX-354,CCX354
Ethanone, 1-[4-(4-chloro-3-methoxyphenyl)-1-piperazinyl]-2-[3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]- | [Molecular Formula]
C22H22ClN7O2 | [MDL Number]
MFCD18633265 | [MOL File]
1010073-75-2.mol | [Molecular Weight]
451.909 |
| Chemical Properties | Back Directory | [Boiling point ]
778.4±60.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
11.27±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
CCX354 is an antagonist of CCR1, with anti-inflammatory activity. | [in vivo]
In vivo, CCX354 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties[1]. | [IC 50]
CCR1 | [storage]
Store at -20°C | [References]
[1] Compounds for the treatment of osteoporosis and cancers. US 20100113472 A1 |
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cjbscvictory
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13348960310 |
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https://www.weikeqi-biotech.com/ |
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