| Identification | Back Directory | [Name]
DIETHYL (2-CYANOETHYL)PHOSPHONATE 95 | [CAS]
10123-62-3 | [Synonyms]
Ai3-16155
NSC 43781
NSC 74863
Brn 1775584
Einecs 233-327-4
Diethyl 2-cyanoethanephosphona
Diethyl 2-cyanoethanephosphonate
3-(Diethylphosphono)propionitrile
3-Diethoxyphosphorylpropanenitrile
Diethyl (2-cyanoethyl)phosphonate 95%
3-(Diethoxyphosphinyl)propiononitrile
DIETHYL (2-CYANOETHYL)PHOSPHONATE 95
beta-(Diethoxyphosphinyl)propionitrile
2-cyanoethanephosphonicaciddiethylester
2-cyano-ethanephosphonicacidiethylester
Ethanephosphonic acid, 2-cyano-, diethyl ester
Phosphonic acid, P-(2-cyanoethyl)-, diethyl ester | [EINECS(EC#)]
233-327-4 | [Molecular Formula]
C7H14NO3P | [MDL Number]
MFCD00013825 | [MOL File]
10123-62-3.mol | [Molecular Weight]
191.16 |
| Chemical Properties | Back Directory | [Boiling point ]
110 °C/0.1 mmHg (lit.) | [density ]
1.08 g/mL at 25 °C (lit.) | [refractive index ]
n20/D 1.4380(lit.) | [Fp ]
>230 °F | [storage temp. ]
Store at room temperature | [Appearance]
Colorless to light yellow Liquid | [InChI]
1S/C7H14NO3P/c1-3-10-12(9,11-4-2)7-5-6-8/h3-5,7H2,1-2H3 | [InChIKey]
LDOZIDLMPNCNDI-UHFFFAOYSA-N | [SMILES]
CCOP(=O)(CCC#N)OCC |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3 | [RTECS ]
KI6650000 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
Diethyl (2-cyanoethyl)phosphonate, is a useful reactant used in various chemical synthesis such as in synthesis of lipophilic oxoamides with activity against phospholipase A2, Triose phosphate isomerase of muscle inhibitors, and also in base-catalyzed stereospecific anti-Markovnikov addition. | [Uses]
Reactant for:
- Heteroatom-directed alkyl cyanation of alkynes
- Use as a fluorescent substrate for carbon-phosphorous lyase
- Microwave-assisted cleavage of phosphate, phosphonate, and phorphoramide esters
- Amination and stereoselective olefination for synthesis of HIV-1 antivirals
Reactant for synthesis of:
- Base-catalyzed stereospecific anti-Markovnikov addition reactants
- Lipophilic oxoamides with activity against phospholipase A2
- Triose phosphate isomerase of muscle inhibitors
| [reaction suitability]
reaction type: C-C Bond Formation |
|
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