ChemicalBook--->CAS DataBase List--->1020567-30-9

1020567-30-9

Request For Quotation
1020567-30-9 Structure

1020567-30-9 Structure
IdentificationBack Directory
[Name]

GSK-2324
[CAS]

1020567-30-9
[Synonyms]

GSK-2324
[Molecular Formula]

C29H22Cl2N2O4
[MOL File]

1020567-30-9.mol
[Molecular Weight]

533.4
Chemical PropertiesBack Directory
[Boiling point ]

698.1±55.0 °C(Predicted)
[density ]

1.351±0.06 g/cm3(Predicted)
[pka]

1.21±0.30(Predicted)
Hazard InformationBack Directory
[Description]

GSK2324 is a FXR agonist (EC50 = 50 nM, 102% efficacy).
[Uses]

GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC50 of 120 nM. GSK2324 exhibits t1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively[1].
[References]

[1] Jonathan Y Bass, et al. Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1206-13. DOI:10.1016/j.bmcl.2010.12.089
Spectrum DetailBack Directory
[Spectrum Detail]

GSK-2324(1020567-30-9)1HNMR
1020567-30-9 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226 , 13588875226
Website: www.hzclap.com/en
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Website: www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Tel: 400-901-9800 18611424007
Website: www.bioss.com.cn/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Tel: 18916360931 18916360931
Website: www.amole.com.cn/
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Website: http://www.absin.cn
Company Name: Proteintech China  
Tel: 027-87531629
Website: http://www.ptgcn.com
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Website: http://www.synzest.com
Tags:1020567-30-9 Related Product Information