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10212-13-2

10212-13-2 Structure

10212-13-2 Structure
IdentificationBack Directory
[Name]

3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE
[CAS]

10212-13-2
[Synonyms]

3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE
2'-Deoxy-2'-fluoro-3',5'-di-O-acetyluridine
1-[4-acetyl-3-fluoro-4-hydroxy-5-(1-hydroxy-2-oxopropyl)-2-oxolanyl]pyrimidine-2,4-dione
((2R,3R,4R,5R)-3-Acetoxy-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl acetate
[Molecular Formula]

C13H15FN2O7
[MDL Number]

MFCD09951839
[MOL File]

10212-13-2.mol
[Molecular Weight]

330.27
Chemical PropertiesBack Directory
[Melting point ]

174-177°C
[density ]

1.45±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, Refrigerator, under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

9.39±0.10(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
[References]

[1] Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25. DOI:10.1016/s0165-6147(99)01298-5
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