| Identification | Back Directory | [Name]
ATP synthase inhibitor 1 | [CAS]
1023043-30-2 | [Synonyms]
ATP SYNTHASE INHIBITOR 1
ATP Synthase,ATP synthase inhibitor 1,Inhibitor,inhibit,ATP synthase inhibitor-1,ATP synthase inhibitor1 | [Molecular Formula]
C17H18ClN3O3S2 | [MDL Number]
MFCD32063515 | [MOL File]
1023043-30-2.mol | [Molecular Weight]
411.93 |
| Chemical Properties | Back Directory | [density ]
1.55±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C,unstable in solution, ready to use. | [solubility ]
DMSO: 5 mg/mL (12.14 mM) | [form ]
Solid | [pka]
14.80±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1].
F1/FO-ATP synthase[1] ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex[1]. | [Uses]
ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1]. | [storage]
Store at -20°C,unstable in solution, ready to use. | [References]
[1]. Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61(16):7131-7143. |
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