ChemicalBook--->CAS DataBase List--->1023875-75-3

1023875-75-3

Request For Quotation
1023875-75-3 Structure

1023875-75-3 Structure
IdentificationBack Directory
[Name]

N-(4-{2-[3-(trifluoromethyl)anilino]-1,3-thiazol-4-yl}phenyl)acetamide
[CAS]

1023875-75-3
[Synonyms]

Todalam
Todalam/MS-7520
N-(4-{2-[3-(trifluoromethyl)anilino]-1,3-thiazol-4-yl}phenyl)acetamide
Acetamide, N-[4-[2-[[3-(trifluoromethyl)phenyl]amino]-4-thiazolyl]phenyl]-
[Molecular Formula]

C18H14F3N3OS
[MDL Number]

MFCD00955234
[MOL File]

1023875-75-3.mol
[Molecular Weight]

377.38
Chemical PropertiesBack Directory
[density ]

1.397±0.06 g/cm3(Predicted)
[pka]

14.58±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Tubulin inhibitor 49 (Compound 18) is an inhibitor for tubulin polymerization with an IC50 of 48 μM. Tubulin inhibitor 49 disrupts the cell microtubule network, arrests the cell cycle at G2 phase, and exhibits cytotoxicity (IC50=8.8 μM in HeLa cell)[1].
[References]

[1] Mühlethaler T, et al., Rational Design of a Novel Tubulin Inhibitor with a Unique Mechanism of Action. Angew Chem Int Ed Engl. 2022 Jun 20;61(25):e202204052. DOI:10.1002/anie.202204052
1023875-75-3 suppliers list
Company Name: Shanghai Chaolan Chemical Technology Center  
Telephone: QQ：65489617 13301690235
Website: www.atkchemical.com/
Company Name: ShangHai ChuanQian Chemcial Technique Centre  
Telephone: 15869524721
Website: www.chemicalbook.com/ShowSupplierProductsList68594/0_EN.htm
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Telephone: 15865264761
Website: www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm
Company Name: Nantong Hi-Future Biotechnology Co., Ltd  
Telephone: +86-0513; 18051384581
Website: https://www.chemhifuture.com/
Company Name: Wuhan Augda Biotechnology Co., Ltd  
Telephone: 15071299552
Website: https://www.chemicalbook.com/supplier/24275232/1.htm
Company Name: Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.  
Telephone: +86-027-59232304 15387063101
Website: https://www.yingnor.com/
Company Name: Xianning Shen Lan Biomedical Research and Development Co., Ltd.  
Telephone: 18171815831
Website: http://www.shenlansw.com/
Company Name: Wuhan Acumen Bio-Technology Co.,ltd  
Telephone: 027-027-16602739303 16602739303
Website: www.yjybiochem.com/
Company Name: Henan Inokai New Materials Co., Ltd  
Telephone: 13290191024 13290191024
Website:
Company Name: Shanghai Weijiahe Biotechnology Co., Ltd  
Telephone: 17502176150; 17502176150
Website:
Company Name: TargetMol  
Telephone: 400-821-0310 15002144251
Website: www.targetmol.cn/
Tags:1023875-75-3 Related Product Information
54965-21-8 897016-82-9 474645-27-7 114977-28-5 796073-69-3 61-73-4