10239-34-6

63674-16-8

10239-34-6

General procedure for the synthesis of N,N'-dibenzylidene-1,3-propanediamine from N1,N3-dibenzylidene-1,3-propanediamine: N1,N3-dibenzylidene-1,3-propanediamine (1 eq.) was dissolved in methanol (50 mL), followed by the addition of sodium borohydride (NaBH4, 2 eq.) into a reaction vessel in a portion of the reaction. The reaction mixture was heated to reflux for 15 minutes. Upon completion of the reaction, it was cooled to room temperature and quenched by the slow addition of water (70 mL). The water phase was extracted with dichloromethane (3 x 50 mL). The organic phases were combined, dried with anhydrous potassium carbonate (K2CO3) and concentrated under reduced pressure to remove the solvent to give the target product N,N'-dibenzyl-1,3-propanediamine.