Identification | Back Directory | [Name]
MOUSE IL-4 | [CAS]
102619-80-7 | [Synonyms]
MIL-4 RMIL-4 MOUSE IL-4 MURINE IL-4 MURINE BCGF MURINE BCDF IL-4, MOUSE IL-4 MURINE MURINE BSF-1 REC IL-4 (MURINE) MOUSE INTERLEUKIN-4 MURINE INTERLEUKIN-4 INTERLEUKIN-4, MOUSE INTERLEUKIN-4, MURINE RECOMBINANT MOUSE IL-4 Interleukin-4 from mouse REC INTERLEUKIN-4 (MURINE) MURINE B CELL STIMULATING FACTOR Recombinant Mouse Interleukin-4 INTERLEUKIN-4, MOUSE, RECOMBINANT | [MDL Number]
MFCD00166698 |
Hazard Information | Back Directory | [Uses]
Interleukin-4 from mouse has been used:
- as a component of cell culture media for class switch recombination assay
- to study its therapeutic benefits for mucosal healing
- as a pioglitazone or new peroxisome proliferator-activated receptor agonist (GQ-11)
| [Biochem/physiol Actions]
Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific. |
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