| Identification | Back Directory | [Name]
GAT-211 | [CAS]
102704-40-5 | [Synonyms]
AZ4
AZ-4
AZ 4
GAT-211
GAT211 >=98% (HPLC)
3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
1H-Indole, 3-(2-nitro-1-phenylethyl)-2-phenyl- | [Molecular Formula]
C22H18N2O2 | [MDL Number]
MFCD02165420 | [MOL File]
102704-40-5.mol | [Molecular Weight]
342.39 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 25 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
GAT211, aslo known as AZ-4, is a small molecule CB1 positive allosteric modulator. GAT211 suppresses allodynia and produces synergistic antiallodynic effects with fatty acid amide hydrolase and monoacylglycerol lipase inhibitors in paclitaxel-treated mice. Positive allosteric modulation of CB1-receptor signaling with GAT211shows promise as a safe and effective analgesic strategy that lacks tolerance, dependence, and abuse liability. |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|