Identification | More | [Name]
(S)-Amlodipine | [CAS]
103129-82-4 | [Synonyms]
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)- 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (S)- l-Amlodipine Levoamlodipine Besylate (4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester (S)-Amlodipine Levamlodipine | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C20H25N2O5Cl | [MDL Number]
MFCD09832686 | [Molecular Weight]
408.88 | [MOL File]
103129-82-4.mol |
Chemical Properties | Back Directory | [Melting point ]
102-104°C | [Boiling point ]
527.2±50.0 °C(Predicted) | [density ]
1.227 | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
Solid | [pka]
8.97±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1 | [InChIKey]
HTIQEAQVCYTUBX-KRWDZBQOSA-N | [SMILES]
C(C1=C(NC(=C([C@@H]1C1C=CC=CC=1Cl)C(=O)OC)C)COCCN)(=O)OCC | [CAS DataBase Reference]
103129-82-4(CAS DataBase Reference) |
Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
(S)-Enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer. | [Uses]
(S)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer. | [Definition]
ChEBI: (S)-amlodipine is the (4S)-enantiomer of amlodipine. It is an enantiomer of a (R)-amlodipine. |
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