ChemicalBook--->CAS DataBase List--->103129-82-4

103129-82-4

103129-82-4 Structure

103129-82-4 Structure
IdentificationMore
[Name]

(S)-Amlodipine
[CAS]

103129-82-4
[Synonyms]

3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (S)-
l-Amlodipine
Levoamlodipine Besylate
(4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
(S)-Amlodipine
Levamlodipine
[EINECS(EC#)]

1592732-453-0
[Molecular Formula]

C20H25N2O5Cl
[MDL Number]

MFCD09832686
[Molecular Weight]

408.88
[MOL File]

103129-82-4.mol
Chemical PropertiesBack Directory
[Melting point ]

102-104°C
[Boiling point ]

527.2±50.0 °C(Predicted)
[density ]

1.227
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

Chloroform (Sparingly), Methanol (Slightly)
[form ]

Solid
[pka]

8.97±0.10(Predicted)
[color ]

White to Off-White
[Major Application]

pharmaceutical
[InChI]

InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1
[InChIKey]

HTIQEAQVCYTUBX-KRWDZBQOSA-N
[SMILES]

C(C1=C(NC(=C([C@@H]1C1C=CC=CC=1Cl)C(=O)OC)C)COCCN)(=O)OCC
[CAS DataBase Reference]

103129-82-4(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
STOT RE 2
Hazard InformationBack Directory
[Chemical Properties]

White to Off-White Solid
[Uses]

(S)-Enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
[Uses]

(S)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
[Definition]

ChEBI: (S)-amlodipine is the (4S)-enantiomer of amlodipine. It is an enantiomer of a (R)-amlodipine.
Spectrum DetailBack Directory
[Spectrum Detail]

(S)-Amlodipine(103129-82-4)1HNMR
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