| Identification | Back Directory | [Name]
ETHYL TETRAHYDROPYRAN-4-YL-ACETATE | [CAS]
103260-44-2 | [Synonyms]
2-(4-oxanyl)butanoate
ethyl 2-(oxan-4-yl)acetate
Ethyl tetrahydropyranyl-4...
Ethyl tetrahydropyran-4-acetate
Ethyl tetrahydropyranyl-4-acetate
Ethyl 2-(tetrahydro-2H-pyran-4-yl)
ETHYL TETRAHYDROPYRAN-4-YL-ACETATE
Ethyl tetrahydro-2H-pyran-4-acetate
Ethyl 2-(4-Tetrahydropyranyl)acetate
tetrahydropyran-4-yl-acetate ethyl ester
ETHYL 2-(TETRAHYDRO-2H-PYRAN-4-YL)ACETATE
(Tetrahydropyran-4-yl)acetic acid ethyl ester
Pyran-4-acetic acid, tetrahydro-, ethyl ester
2H-Pyran-4-acetic acid, tetrahydro-, ethyl ester | [Molecular Formula]
C9H16O3 | [MDL Number]
MFCD03788560 | [MOL File]
103260-44-2.mol | [Molecular Weight]
172.22 |
| Chemical Properties | Back Directory | [Boiling point ]
73-75 0,2mm | [density ]
1.0268 g/cm3(Temp: 13.4 °C) | [refractive index ]
1.4572 (13.4℃) | [storage temp. ]
Inert atmosphere,Room Temperature | [Appearance]
Colorless to light yellow Liquid | [CAS DataBase Reference]
103260-44-2 |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of ethyl tetrahydropyran-4-yl-acetate from ethyl 2-(dihydro-2H-pyran-4(3H)-ylidene)acetate: ethyl tetrahydro-4H-pyran-4-ylidene acetate (16.0 g, 94 mmol) was reacted with Pd/NH4COOH at 80 °C to give the colorless oily product ethyl tetrahydropyran-4-yl-acetate. Yield: 16.3 g (quantitative), mass spectral (MS) data: m/z 173.2 ([M + H]+). | [References]
[1] Journal of Medicinal Chemistry, 2004, vol. 47, # 25, p. 6255 - 6269
[2] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 23, p. 6309 - 6323
[3] Patent: US6340691, 2002, B1. Location in patent: Page column 66
[4] Patent: EP1147080, 2004, B1. Location in patent: Page 49
[5] Patent: WO2013/37960, 2013, A1. Location in patent: Page/Page column 76 |
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