| Identification | Back Directory | [Name]
Tepoxalin | [CAS]
103475-41-8 | [Synonyms]
epoxalin
Tepoxalin
RWJ-20485
ORF 20485
inhibit,Lipoxygenase,LOX,Inhibitor,COX,Tepoxalin,Cyclooxygenase
5-(4-Chlorophenyl)-N-hydroxy-1-(4-Methoxyphenyl)-N-Methyl-1H-pyrazole-3-propanaMide
1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-
3-(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl)-N-hydroxy-N-methylpropanamide
3-[1-(4-Methoxyphenyl)-5-(4-chlorophenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide | [Molecular Formula]
C20H20ClN3O3 | [MDL Number]
MFCD00866620 | [MOL File]
103475-41-8.mol | [Molecular Weight]
385.849 |
| Chemical Properties | Back Directory | [Melting point ]
124-126° | [storage temp. ]
Hygroscopic, Refrigerator, Under Inert Atmosphere | [solubility ]
DMSO (Sparingly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Pale Brown | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Tepoxalin is non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity a s well as inhibiting the production of cytokines in peripheral cells outside the CNS.
| [Definition]
ChEBI: A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the contr
l of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs. | [Veterinary Drugs and Treatments]
Tepoxalin is indicated for the treatment of pain and inflammation
associated with osteoarthritis in dogs. Because of the drug’s inhibitory
effects on leukotrienes, there is interest in seeing if it would
be beneficial in the adjunctive treatment of allergic conditions in
dogs. |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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