ChemicalBook--->CAS DataBase List--->103476-21-7

103476-21-7

103476-21-7 Structure

103476-21-7 Structure
IdentificationBack Directory
[Name]

(DL-3-HYDROXY-3-METHYLGLUTARYL) COENZYM&
[CAS]

103476-21-7
[Synonyms]

XCMQYNRDGHLEPX-FZFZRPSRSA-L
(DL-3-HYDROXY-3-METHYLGLUTARYL) COENZYM&
DL-3-HYDROXY-3-METHYLGLUTARYL COENZYME*A SODIUM
DL-3-Hydrxy-3-methylglutaryl-coenzym A Natriumsalz
DL-3-Hydroxy-3-methylglutaryl coenzyme A (disodium)
DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt
(DL-3-hydroxy-3-methylglutaryl)coenzyme A disodium hydrate
DL-3-Hydroxy-3-methylglutaryl coenzymeA sodium salt,HMG-CoA
(dl-3-hydroxy-3-methylglutaryl) coenzyme A so-salt trihydr.
DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt hydrate
(DL-3-HYDROXY-3-METHYLGLUTARYL) COENZYME A DISODIUM SALT, 95%
Coenzyme A S-(hydrogen 3-hydroxy-3-methyl pentanedioate) disodium salt
(DL-3-Hydroxy-3-methylglutaryl)-coenzyme A trihydrate disodium salt
(DL-3-Hydroxy-3-methylglutaryl)-coenzyme A disodium salt trihydrate,HMG-CoA
Coenzyme A, S-(hydrogen3-hydroxy-3-methyl pentanedioate), disodium salt (9CI)
[Molecular Formula]

C27H42N7O20P3S.2Na
[MDL Number]

MFCD17215980
[MOL File]

103476-21-7.mol
[Molecular Weight]

955.626
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

H2O: 50 mg/mL, clear, faintly yellow
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10-21
Hazard InformationBack Directory
[Uses]

DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt hydrate has been used in drug treatment to study its effect on mTORC1 regulation. It has also been used to compare the acylomes of two reactive acyl-CoA species, like HMG-CoA and?glutaryl-CoA.
[General Description]

DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)?is obtained from acetyl-CoA?and?acetoacetyl-CoA during condensation with the help of HMG-CoA synthase.
[Biochem/physiol Actions]

DL-3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) is a substrate used to study the specificity and kinetics of the enzyme 3-hydroxyl-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase. HMG-CoA is the key intermediate in the biosynthsis of terpenes and ketone bodies. Its metabolism is the target of statin drugs used to control cholesterol levels.
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