ChemicalBook--->CAS DataBase List--->28728-55-4

28728-55-4

28728-55-4 Structure

28728-55-4 Structure
IdentificationBack Directory
[Name]

HEXADIMETHRINE BROMIDE
[CAS]

28728-55-4
[Synonyms]

POLYBRENE
6,3-ionene
sequa-brene
POLYBRENE (R))
SEQUA-BRENE(TM)
6,3-ionenebromide
HEXADIMETHRIN BROMIDE
HEXADIMETHRINE BROMIDE
HEXADIMETHRINE BROMIDE, >=95%
Sequa-brene,Hexadimethrine bromide, Polybrene
HEXADIMETHRIN BROMIDE, FOR PROTEIN SEQUE NCE ANALYSIS
1,5-DIMETHYL-1,5-DIAZAUNDECAMETHYLENE POLYMETHOBROMIDE
poly((dimethyliminio)hexamethylene(dimethylimino)trimethylenedibromide)
POLY(N,N,N',N'-TETRAMETHYL-N-TRIMETHYLENEHEXAMETHYLENEDIAMMONIUM DIBROMIDE)
Poly(dimethyliminio)-1,3-propanediyl(dimethyliminio)-1,6-hexanediyl dibromide
Hexadimethrine bromide,1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene
[Molecular Formula]

C39H90Br6N6X2
[MDL Number]

MFCD00133397
[MOL File]

28728-55-4.mol
[Molecular Weight]

1122.6
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow
[form ]

gelatinous solid
[color ]

White to off-white
[Water Solubility ]

10mg/ml in Water
[Merck ]

13,4702
[CAS DataBase Reference]

28728-55-4
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[RIDADR ]

2811
[WGK Germany ]

3
[RTECS ]

TQ2655000
[F ]

3-10
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[Toxicity]

Polymers with mol wt of 5000-10,000 have LD50 i.v. in mice: 25-40 mg/kg (Kimura)
Hazard InformationBack Directory
[Uses]

Antiheparin agent. A 3mg quantity has been found to enhance peptide degradation in automated sequential analysis.
[Uses]

Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections.
Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant.
[Uses]

Used as a protein/peptide carrier for protein sequencing.
[Definition]

ChEBI: Hexadimethrine bromide is a polymer.
[General Description]

Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA.
[storage]

Store at 2-8℃, stored under nitrogen
[Purification Methods]

Purify it by chromatography on Dowex 50 and/or by filtration through alumina before use [Frank Hoppe-Seyler's Z Physiol Chemie 360 997 1979]. It is hygroscopic, and its solubility in H2O is 10%.
Spectrum DetailBack Directory
[Spectrum Detail]

HEXADIMETHRINE BROMIDE(28728-55-4)IR1
HEXADIMETHRINE BROMIDE(28728-55-4)IR2
HEXADIMETHRINE BROMIDE(28728-55-4)Raman
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