| Identification | Back Directory | [Name]
Carbamic acid, N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester | [CAS]
1035490-58-4 | [Synonyms]
(S)-2-(Boc-amino)-2-(3-fluorophenyl)ethanol
tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate
tert-butyl N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]carbamate
(S)-1-(3-fluoro-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester
Carbamic acid, N-[(1S)-1-(3-fluorophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C13H18FNO3 | [MOL File]
1035490-58-4.mol | [Molecular Weight]
255.29 |
| Hazard Information | Back Directory | [Physical properties]
A white crystal,melting point:106.5 - 107.9
| [Uses]
Useful research chemical for a range of applications. | [Preparation]
Amino alcohol hydrochloride (192.22 mmol) and di-f-butyl dicarbonate (262.63 mmol, 1.37 eq) were suspended in f-BuOH (250 mL, 6.25 volumes) and then treated with aqueous 2 N NaOH (120 mL, 240 mmol). The contents were warmed to 75 °C (immediate effervescence was observed) for 4 h. The internal temp was then reduced to 50 °C, and the contents were added to water (2 L) with vigorous stirring. Tert-butyl (S)-(1-(3-fluorophenyl)-2-hydroxyethyl)carbamate was obtained after purification.
 |
|
|