| Identification | Back Directory | [Name]
ACETYL AF-64 | [CAS]
103994-00-9 | [Synonyms]
ACETYL AF-64
ACETYLETHYLCHOLINE MUSTARD HYDROCHLORIDE | [Molecular Formula]
C8H17Cl2NO2 | [MDL Number]
MFCD00055153 | [MOL File]
103994-00-9.mol | [Molecular Weight]
230.13 |
| Chemical Properties | Back Directory | [Melting point ]
78-81 °C | [Fp ]
96 °C | [storage temp. ]
-20°C | [solubility ]
H2O: soluble | [form ]
solid | [color ]
white | [Water Solubility ]
H2O: >5mg/mL
ethanol: soluble
methanol: soluble | [InChI]
1S/C8H16ClNO2.ClH/c1-3-10(5-4-9)6-7-12-8(2)11;/h3-7H2,1-2H3;1H | [InChIKey]
CHWPASAPXMNLKO-UHFFFAOYSA-N | [SMILES]
Cl[H].CCN(CCCl)CCOC(C)=O |
| Hazard Information | Back Directory | [Uses]
Acetylethylcholine Mustard Hydrochloride is a reagent used in the synthesis of 2-[N-(ethyl)-(N-β-hydroxyethyl)]aminoethyl 2,2-diphenylpropionate, a metabolite of aprophen which is an antimuscarinic agent. | [Biological Activity]
Acetylethylcholine mustard hydrochloride can reduce the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM.''Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase. |
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SIGMA-RBI
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