| Identification | Back Directory | [Name]
2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole | [CAS]
1067883-58-2 | [Synonyms]
CM-Phos
2-[2-(Dicyclohexylphosphino)phenyl]-N-methylindole
2-(2-(dicyclohexylphosphino)phenyl)-1-Methyl-indole
2-(2-Dicyclohexylphosphanyl-phenyl)-1-Methyl-1H-indole
2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole
2-[2-(Dicyclohexylphosphino)phenyl]-1-Methyl-1H-indole, Min. 98% CM-Phos | [Molecular Formula]
C27H34NP | [MDL Number]
MFCD16995285 | [MOL File]
1067883-58-2.mol | [Molecular Weight]
403.539 |
| Chemical Properties | Back Directory | [Melting point ]
180-185℃ | [Boiling point ]
582.4±33.0 °C(Predicted) | [form ]
Powder | [color ]
white to off-white | [InChI]
1S/C27H34NP/c1-28-25-18-10-8-12-21(25)20-26(28)24-17-9-11-19-27(24)29(22-13-4-2-5-14-22)23-15-6-3-7-16-23/h8-12,17-20,22-23H,2-7,13-16H2,1H3 | [InChIKey]
PFJAHDIIEPTASS-UHFFFAOYSA-N | [SMILES]
Cn1c(cc2ccccc12)-c3ccccc3P(C4CCCCC4)C5CCCCC5 | [CAS DataBase Reference]
1067883-58-2 |
| Questions And Answer | Back Directory | [Reaction]
- Suzuki-Miyaura Coupling of Aryl Mesylates and alkenyl tosylate and mesylate bearing alkyl, methoxy, aldehyde, keto, nitrile, ester, and heteroaryl substitution.
- Sonogashira Coupling of Aryl Mesylates, R' = alkyl, aryl; R = C(O)R, COOMe, CHO, CN.
- Buchwald-Hartwig Amination of Aryl Mesylates, R = cyano, chloro, methoxy, keto, ester and etc.
- Additional catalyzed reactions include Cyanation of functional Aryl Mesylates and Chlorides; Hiyama Coupling of Aryl Mesylates; Direct Arylation of Heterocycles with Aryl Mesylates; Borylation of Aryl Mesylates.
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| Hazard Information | Back Directory | [Uses]
2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole (CM-Phos) is an organic compound with catalytic activity. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole can be used as an efficient catalyst for cross-coupling reactions of various alcohols and olefins. 2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole shows important application potential in pharmaceutical and material science. | [reaction suitability]
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand | [Synthesis]
2-(2-DicyclohexylphosphaNYL-phenyl)-1-methyl-1H-indole can be prepared in one step from N-methyl-2-phenyl-3-bromoindole with chlorodicyclohexylphosphine.
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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LaaJoo
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021-60702684 18516024827 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList20079/0_EN.htm |
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