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106900-12-3

106900-12-3 Structure

106900-12-3 Structure
IdentificationBack Directory
[Name]

Loperamide
[CAS]

106900-12-3
[Synonyms]

R 58425
loperamide oxide
LoperaMide-d6 N-Oxide
trans-Loperamide N-Oxide
Loperamide EP Impurity F
Loperamide impurity-F(EP)
Loperamide EP Impurity F HCl
Loperamide oxide monohydrate CRS
Loperamide USP Related Compound F
Loperamide Hydrochloride Impurity F
Loperamide Hydrochloride EP Impurity F
Loperamide Impurity 6(Loperamide EP Impurity F)
Loperamide EP Impurity F/ Loperamide Related Compound F (Loperamide N-Oxide)
4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide
1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, 1-oxide, trans-
trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide
trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate
Loperamide Related Compound F ((1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbu (1370065)
4-[TRANS-4-(4-CHLOROPHENYL)-4-HYDROXY-1- OXIDOPIPERIDIN-1-YL]-N,N-DIMETHYL-2,2- DIPHENYLBUTANAMIDE HYDROCHLORIDE
Loperamide N-oxideQ: What is Loperamide N-oxide Q: What is the CAS Number of Loperamide N-oxide Q: What is the storage condition of Loperamide N-oxide Q: What are the applications of Loperamide N-oxide
[Molecular Formula]

C29H33ClN2O3
[MDL Number]

MFCD00870596
[MOL File]

106900-12-3.mol
[Molecular Weight]

493.044
Chemical PropertiesBack Directory
[Appearance]

White or almost white powder, slightly hygroscopic.
[storage temp. ]

2-8°C
[solubility ]

Practically insoluble in water, freely soluble in alcohol and in methylene chloride.
[form ]

neat
[pka]

12.94±0.20(Predicted)
[Stability:]

Hygroscopic
[Major Application]

pharmaceutical
[InChI]

1S/C29H33ClN2O3/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32(35)20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3
[InChIKey]

KXVSBTJVTUVNPM-UHFFFAOYSA-N
[SMILES]

Clc1ccc(cc1)C2(CC[N](=O)(CC2)CCC(c4ccccc4)(c3ccccc3)C(=O)N(C)C)O
Hazard InformationBack Directory
[Chemical Properties]

White or almost white powder, slightly hygroscopic.
[Uses]

Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
[Uses]

Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.
[Definition]

ChEBI: Loperamide oxide is a diarylmethane.
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P405-P501
[RIDADR ]

UN 2811 6.1 / PGIII
[WGK Germany ]

WGK 1
[RTECS ]

TM4960200
[HS Code ]

2933399090
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 3 Oral
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