| Identification | Back Directory | [Name]
Loperamide | [CAS]
106900-12-3 | [Synonyms]
R 58425
loperamide oxide
LoperaMide-d6 N-Oxide
trans-Loperamide N-Oxide
Loperamide EP Impurity F
Loperamide impurity-F(EP)
Loperamide EP Impurity F HCl
Loperamide oxide monohydrate CRS
Loperamide USP Related Compound F
Loperamide Hydrochloride Impurity F
Loperamide Hydrochloride EP Impurity F
Loperamide Impurity 6（Loperamide EP Impurity F）
Loperamide EP Impurity F/ Loperamide Related Compound F (Loperamide N-Oxide)
4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide
1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-, 1-oxide, trans-
trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide
trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate
Loperamide Related Compound F ((1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbu (1370065)
4-[TRANS-4-(4-CHLOROPHENYL)-4-HYDROXY-1-
OXIDOPIPERIDIN-1-YL]-N,N-DIMETHYL-2,2-
DIPHENYLBUTANAMIDE HYDROCHLORIDE
Loperamide N-oxideQ: What is
Loperamide N-oxide Q: What is the CAS Number of
Loperamide N-oxide Q: What is the storage condition of
Loperamide N-oxide Q: What are the applications of
Loperamide N-oxide | [Molecular Formula]
C29H33ClN2O3 | [MDL Number]
MFCD00870596 | [MOL File]
106900-12-3.mol | [Molecular Weight]
493.044 |
| Chemical Properties | Back Directory | [Appearance]
White or almost white powder, slightly hygroscopic. | [storage temp. ]
2-8°C | [solubility ]
Practically insoluble in water, freely soluble in alcohol and in methylene chloride. | [form ]
neat | [pka]
12.94±0.20(Predicted) | [Stability:]
Hygroscopic | [Major Application]
pharmaceutical | [InChI]
1S/C29H33ClN2O3/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32(35)20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 | [InChIKey]
KXVSBTJVTUVNPM-UHFFFAOYSA-N | [SMILES]
Clc1ccc(cc1)C2(CC[N](=O)(CC2)CCC(c4ccccc4)(c3ccccc3)C(=O)N(C)C)O |
| Hazard Information | Back Directory | [Chemical Properties]
White or almost white powder, slightly hygroscopic. | [Uses]
Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon. | [Uses]
Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon. | [Definition]
ChEBI: Loperamide oxide is a diarylmethane. |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301 | [Precautionary statements ]
P264-P270-P301+P310-P405-P501 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
WGK 1 | [RTECS ]
TM4960200 | [HS Code ]
2933399090 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
|
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BOC Sciences
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16314854226 |
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www.bocsci.com |
| Company Name: |
TOSUN PHARM
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www.toref.cn/ |
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