| Identification | Back Directory | [Name]
LOXIGLUMIDE | [CAS]
107097-80-3 | [Synonyms]
CS-162
cr1505
anoicacid
ntanoicacid
LOXIGLUMIDE
(+-)--5-oxo
Loxiglumide, >98%
LoxigluMide (CR1505)
Loxiglumide >=97% (HPLC)
d,l-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pent
(+-)-4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxope
pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)
5-[amyl(3-methoxypropyl)amino]-4-[(3,4-dichlorobenzoyl)amino]-5-keto-valeric acid
4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid
Pentanoic acid, 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-
4-[(3,4-dichlorophenyl)carbonylamino]-5-[3-methoxypropyl(pentyl)amino]-5-oxo-pentanoic acid | [Molecular Formula]
C21H30Cl2N2O5 | [MDL Number]
MFCD00866772 | [MOL File]
107097-80-3.mol | [Molecular Weight]
461.38 |
| Chemical Properties | Back Directory | [Melting point ]
113-115℃ | [Boiling point ]
632.2±55.0 °C(Predicted) | [density ]
1.233±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥5mg/mL | [form ]
powder | [pka]
pKa ~5(at 25℃) | [color ]
white to beige | [CAS DataBase Reference]
107097-80-3 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
3 | [Safety Profile]
A poison by
intravenous. Moderately toxic by ingestion,
intraperitoneal, and subcutaneous routes.
When heated to decomposition it emits
toxic vapors of NOx and Cl-. |
| Hazard Information | Back Directory | [Uses]
Loxiglumide is a CCK1 antagonist. Suppresses CCK-induced proliferation of acinar cells. Inhibits pancreatic secretion of digestive enzymes. Active in vivo. | [Definition]
ChEBI:Loxiglumide is an organic molecular entity. | [Biochem/physiol Actions]
Loxiglumide is a small-molecule antagonist of the cholecystokinin receptor CCKA. Loxiglumide inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. | [storage]
Store at -20°C |
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Sigma-Aldrich
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