| Identification | More | [Name]
PYRIDINE-2-CARBOXALDOXIME METHIODIDE | [CAS]
94-63-3 | [Synonyms]
2-FORMYL-1-METHYLPYRIDINIUM IODIDE OXIME
2-[(HYDROXYIMINO)METHYL]-1-METHYLPYRIDINIUM IODIDE
2-PAM
2-PYRIDINEALDOXIME METHIODIDE
LABOTEST-BB LT00455561
PRALIDOXIME IODIDE
PYRIDINE-2-ALDOXIME METHIODIDE
PYRIDINE-2-CARBOXALDOXIME METHIODIDE
1-methyl-2-aldoximinopyridiniumiodide
1-methyl-2-hydroxyiminomethylpyridiniumiodide
2-formyl-n-methylpyridiniumoximeiodide
2-pamiodide
2-pyridinaldoximmethojodid
2-pyridinealdoximeiodomethylate
n-methylpyridine-2-aldoximeiodide
n-methylpyridinium-2-aldoximeiodide
nsc-7760
p-2-am
pralidoximemethiodide
protopamiodide | [EINECS(EC#)]
202-349-6 | [Molecular Formula]
C7H9IN2O | [MDL Number]
MFCD00011982 | [Molecular Weight]
264.06 | [MOL File]
94-63-3.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
UU4375000
| [HS Code ]
29333990 | [Safety Profile]
Poison by subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Moderately toxic by ingestion. Used as an antidote to the cholinesterase inhibitors of the parathion group. When heated to decomposition it emits highly toxic fumes of NO, and I-. | [Toxicity]
LD50 in mice (mg/kg): 140-178 i.v., 136-260 i.p., 290-340 s.c., 1500-4000 orally (Ellin, Wills) |
| Hazard Information | Back Directory | [Uses]
Cholinesterase reactivator. | [Definition]
ChEBI: An organic iodide salt that has pralidoxime as the cation. | [in vivo]
Pralidoxime iodide (10-150 mg/kg; intramuscular administration, once) reverses paraoxon-induced respiratory toxicity in mice[3]. | Animal Model: | Male F1B6D2 mice (toxic but non-lethal model of diethylparaoxon in awake, unrestrained mice)[3] | | Dosage: | 10, 50, 100 and 150 mg/kg | | Administration: | Intramuscularly, once | | Result: | Induced a partial, albeit complete, reversal of respiratory toxicity at 50 mg/kg, and completely reversed diethylparaoxon-induced respiratory toxicity in mice at 150 mg/kg. |
| [IC 50]
AChE |
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