| Identification | More | [Name]
3,3-Tetramethyleneglutarimide | [CAS]
1075-89-4 | [Synonyms]
3,3-TETRAMETHYLENEGLUTARIMIDE
8-AZASPIRO[4,5]DECANE-7,9-DIONE
BETA,BETA-TETRAMETHYLENEGLUTARIMIDE
LABOTEST-BB LT00233142
TETRAMETHYLENE GLUTARIMIDE
1,1-cyclopentanediacetimide
1,1-cyclopentanedlacetimide
AZA-8
1,1-CYCLOPENTANEDIACETAMIDE ( CYPIM )
3,3-Tetramethyleneglutarimide, 98+%
Tetramethylene glutarimide,99% | [EINECS(EC#)]
427-770-4 | [Molecular Formula]
C9H13NO2 | [MDL Number]
MFCD00023871 | [Molecular Weight]
167.21 | [MOL File]
1075-89-4.mol |
| Questions And Answer | Back Directory | [Synthesis]
CN92108607.5 reports a novel preparation method for 3,3-tetramethyleneglutarimide: 1,1-cyclopentanediacetic acid and urea are mixed in a ratio of 1:1.1-1:1.6 (molar ratio) and stirred at 150-200℃ for 0.5-2 hours. After the reaction, crude 8-azaspiro[4,5]decane-7,9-dione compound is obtained. Then, it is recrystallized with 30-60% ethanol and activated carbon to obtain white crystalline 3,3-tetramethyleneglutarimide compound with a yield of 80.1-89.5% and a melting point of 154-156℃. The urea used is a readily available and inexpensive raw material. Furthermore, because acetic anhydride is not used, there are no special requirements for the reaction equipment. At the same time, the method of this invention simplifies the reaction steps compared to existing technologies. Therefore, this invention has the advantages of low raw material costs, simple equipment, and short reaction time. It is particularly suitable for industrial production. |
| Chemical Properties | Back Directory | [Appearance]
white to off-white crystalline powder | [Melting point ]
153-155 °C
| [Boiling point ]
295.79°C (rough estimate) | [density ]
1.1222 (rough estimate) | [refractive index ]
1.4760 (estimate) | [storage temp. ]
Poison room | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
powder to crystal | [pka]
11.71±0.20(Predicted) | [color ]
White to Almost white | [BRN ]
383702 | [Major Application]
pharmaceutical (small molecule) | [InChI]
InChI=1S/C9H13NO2/c11-7-5-9(3-1-2-4-9)6-8(12)10-7/h1-6H2,(H,10,11,12) | [InChIKey]
YRTHJMQKDCXPAY-UHFFFAOYSA-N | [SMILES]
C1C2(CC(=O)NC(=O)C2)CCC1 | [CAS DataBase Reference]
1075-89-4(CAS DataBase Reference) | [NIST Chemistry Reference]
1,1-Cyclopentanediacetimide(1075-89-4) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS06,GHS09 | [Signal word ]
Danger | [Hazard statements ]
H301-H411 | [Precautionary statements ]
P264-P270-P273-P301+P310-P391-P405 | [Hazard Codes ]
T+ | [Risk Statements ]
R28:Very Toxic if swallowed. | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
WGK 3 | [REACH Registrations]
Active | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29251995 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Aquatic Chronic 2 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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