ChemicalBook--->CAS DataBase List--->108-43-0

108-43-0

108-43-0 Structure

108-43-0 Structure
IdentificationMore
[Name]

3-Chlorophenol
[CAS]

108-43-0
[Synonyms]

3-CHLOROPHENOL
CHLOROPHENOL(M-)
M-CHLOROPHENOL
3-chloro-1-hydroxybenzene
3-chloro-pheno
3-Hydroxychlorobenzene
m-chlorophenicacid
m-chloro-pheno
meta-Chlorophenol
Phenol, m-chloro-
Phenol,3-chloro-
3-Chlorophenol m-Chlorophenol
3-CHLOROPHENOL PESTANAL
3-Chlorophenol,>98%
MONOCHLOROPHENOL
3-MONOCHLOROPHENOL
3-Chlorphenol
3-Chloro-1-benzenol
3-Cl-phenol
[EINECS(EC#)]

203-582-6
[Molecular Formula]

C6H5ClO
[MDL Number]

MFCD00002256
[Molecular Weight]

128.56
[MOL File]

108-43-0.mol
Chemical PropertiesBack Directory
[Appearance]

All isomers have a characteristic odor.
[Melting point ]

31-34 °C (lit.)
[Boiling point ]

214 °C (lit.)
[density ]

1.218 g/mL at 25 °C(lit.)
[vapor pressure ]

1 hPa (44 °C)
[refractive index ]

n20/D 1.563(lit.)
[Fp ]

>230 °F
[storage temp. ]

2-8°C
[solubility ]

Soluble in ethanol and ether.
[form ]

Liquid After Melting
[pka]

8.85(at 25℃)
[color ]

Clear yellow to brownish
[Odor]

distinct phenol-like odor
[PH]

3.5 (27.7g/l, H2O, 20℃)
[Stability:]

Stable. Combustible. Incompatible with acid chlorides, oxidizing agents, acid anhydrides. Discolours in air.
[Water Solubility ]

27.7 g/L (20 ºC)
[Detection Methods]

GC
[Merck ]

14,2154
[BRN ]

1634401
[InChI]

1S/C6H5ClO/c7-5-2-1-3-6(8)4-5/h1-4,8H
[InChIKey]

HORNXRXVQWOLPJ-UHFFFAOYSA-N
[SMILES]

Oc1cccc(Cl)c1
[CAS DataBase Reference]

108-43-0(CAS DataBase Reference)
[NIST Chemistry Reference]

Phenol, 3-chloro-(108-43-0)
[EPA Substance Registry System]

108-43-0(EPA Substance)
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Exclamation Mark (GHS07)Environment (GHS09)
GHS05,GHS07,GHS09
[Signal word ]

Danger
[Hazard statements ]

H302+H312+H332-H315-H318-H411
[Precautionary statements ]

P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
[Hazard Codes ]

Xn,N
[Risk Statements ]

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[Safety Statements ]

S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
[RIDADR ]

UN 2020 6.1/PG 3
[WGK Germany ]

2
[RTECS ]

SK2450000
[F ]

9
[Autoignition Temperature]

>600 °C
[TSCA ]

Yes
[HazardClass ]

6.1
[PackingGroup ]

III
[HS Code ]

29081000
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Dam. 1
Skin Irrit. 2
[Safety Profile]

Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Questionable carcinogen with experimental tumorigenic data by skin contact. Mutation data reported. Flammable or combustible liquid. When heated to decomposition it emits toxic fumes of Cl-. See also CHLOROPHENOLS.
[Hazardous Substances Data]

108-43-0(Hazardous Substances Data)
[Toxicity]

LD50 orally in rats: 0.57 g/kg (Deichmann)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Sodium nitrite-->Sodium hypochlorite-->Sulfuryl chloride-->4-Chloroaniline-->3-Chloroaniline-->2-Chlorophenol
[Preparation Products]

4-Chloro-2-hydroxybenzaldehyde-->2-Chloro-6-hydroxybenzaldehyde-->3-Chlorophenoxyacetyl chloride-->2,4,6-tribromo 3-chlorophenol-->2,4-dibromo-5-chlorophenol-->3-Chloro-2-iodophenol-->3-Chlorophenoxyacetic acid-->(+)-Cloprostenol-->3-Chloro-4-iodophenol-->2-Bromo-3-chlorophenol
Hazard InformationBack Directory
[General Description]

White crystals with an odor of phenol. Sinks in and slowly dissolves in water.
[Reactivity Profile]

M-CHLOROPHENOL(108-43-0) is incompatible with acid chlorides, acid anhydrides and oxidizing agents .
[Air & Water Reactions]

Discolors on exposure to air. Water soluble
[Hazard]

Toxic by skin absorption, inhalation, or ingestion.
[Potential Exposure]

Monochlorophenols are used in the manufacture of fungicides, slimicides, bactericides, pesticides, herbicides, disinfectants, wood and glue preservatives; in the production of phenolic resins; in the extraction of certain minerals from coal; as a denaturant for ethanol; as an antiseptic; as a disinfectant, and others.
[Fire Hazard]

This chemical is probably combustible.
[First aid]

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.
[Shipping]

UN 2020 (solid); UN2021 (liquid) Chlorophenols, solid and liquid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
[Incompatibilities]

May form explosive mixture with air. Contact with oxidizing agents can cause fire and explosion hazard. Heat produces hydrogen chloride and chlorine. Corrosive to aluminum, copper and other chemically active metals.
[Chemical Properties]

All isomers have a characteristic odor.
[Chemical Properties]

White to light yellow crystal.
[Waste Disposal]

Incinerate in admixture with flammable solvent in furnace equipped with afterburner and scrubber.
[Uses]

3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlo rophenol can be used in the regeneration of vegetal activated carbons.
[Definition]

ChEBI: 3-chlorophenol is a monochlorophenol carrying the chloro substituent at position 3.
[Purification Methods]

It could not be obtained solid by crystallisation from pet ether. It is best purified by distillation under reduced pressure. [Beilstein 6 IV 810.]
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

3-Chlorophenol(108-43-0).msds
Spectrum DetailBack Directory
[Spectrum Detail]

3-Chlorophenol(108-43-0)MS
3-Chlorophenol(108-43-0)1HNMR
3-Chlorophenol(108-43-0)13CNMR
3-Chlorophenol(108-43-0)IR1
3-Chlorophenol(108-43-0)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

3-Chlorophenol, 99%(108-43-0)
[Alfa Aesar]

3-Chlorophenol, 98+%(108-43-0)
[Sigma Aldrich]

108-43-0(sigmaaldrich)
[TCI AMERICA]

3-Chlorophenol,>98.0%(GC)(108-43-0)
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