| Identification | Back Directory | [Name]
HEXYL GALLATE | [CAS]
1087-26-9 | [Synonyms]
HEXYL GALLATE
Gallic acid hexyl ester
Hexyl 3,4,5-trihydroxybenzoate
N-HEXYL 3,4,5-TRIHYDROXYBENZOATE
3,4,5-Trihydroxybenzoic acid hexyl ester
Benzoic acid, 3,4,5-trihydroxy-, hexyl ester | [Molecular Formula]
C13H18O5 | [MDL Number]
MFCD00051936 | [MOL File]
1087-26-9.mol | [Molecular Weight]
254.28 |
| Chemical Properties | Back Directory | [Melting point ]
92 °C | [Boiling point ]
465.9±40.0 °C(Predicted) | [density ]
1.239±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 41.67 mg/mL (163.87 mM) | [form ]
Solid | [pka]
7.96±0.25(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR[1]. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM[2]. | [IC 50]
Plasmodium | [storage]
Store at -20°C | [References]
[1] Kim B, et al. Differential effects of alkyl gallates on quorum sensing in Pseudomonas aeruginosa. Sci Rep. 2019;9(1):7741. Published 2019 May 23. DOI:10.1038/s41598-019-44236-w
[2] Ade Arsianti, et al. Synthesis and in vitro antimalarial activity of alkyl esters of gallate as a growth inhibitor of plasmodium falciparum. Oriental Journal of Chemistry, 34(2), 655-662.
[3] Cavalca LB, et al. Hexyl gallate for the control of citrus canker caused by Xanthomonas citri subsp citri [published online ahead of print, 2020 Aug 6]. Microbiologyopen. 2020;e1104. DOI:10.1002/mbo3.1104 |
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