ChemicalBook--->CAS DataBase List--->109351-34-0

109351-34-0

109351-34-0 Structure

109351-34-0 Structure
IdentificationBack Directory
[Name]

(R)-Terazosin
[CAS]

109351-34-0
[Synonyms]

(R)-Terazosin
Terazosin-002-R
(R)-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (R)-
Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(2R)-tetrahydro-2-furanyl]-
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[[(2R)-tetrahydro-2-furanyl]carbonyl]- (9CI)
[Molecular Formula]

C19H25N5O4
[MOL File]

109351-34-0.mol
[Molecular Weight]

387.43
Chemical PropertiesBack Directory
[Boiling point ]

664.5±65.0 °C(Predicted)
[density ]

1.332±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 75 mg/mL (193.58 mM)
[form ]

Solid
[pka]

6.52±0.50(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

(R)-Terazosin is an single stereoisomer of Terazosin Hydrochloride (T105000), an α-1-adrenergicblocker related to prazosin.
[in vivo]

(R)-Terazosin shows antagonism of at rat atrial α2B receptor with a pEC30 of 5.69. (R)-Terazosin shows antagonism of at rat vas deferens α1A and α2A receptor with pA2 values of 7.5 and 5.31, respectively[1].

[storage]

Store at -20°C
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