| Identification | Back Directory | [Name]
1,1'-METHYLENEDI-2-NAPHTHOL | [CAS]
1096-84-0 | [Synonyms]
SQUOXIN
AKOS BBS-00002910
1,1’-methylenedi-2-naphtho
1,1'-METHYLENEDI-2-NAPHTHOL
1,1-METHYLENE-DI-2-NAPHTHOL
METHYLENE-1,1'-DI-2-NAPHTHOL
1,1'-METHYLENEBIS(2-NAPHTHOL)
Bis(2-hydroxy-1-naphtyl)methane
1,1-Methylene-di-2-naphthol,98%
BIS(2-HYDROXY-1-NAPHTHYL)METHANE
1,1'-Methylenebis(naphthalen-2-ol)
[1,1'-Methylenebisnaphthalene]-2,2'-diol
Bis(2-hydroxy-1-naphthyl)methane
1,1'-Methylenebis(2-naphthol) | [EINECS(EC#)]
214-145-4 | [Molecular Formula]
C21H16O2 | [MDL Number]
MFCD00046470 | [MOL File]
1096-84-0.mol | [Molecular Weight]
300.35 |
| Chemical Properties | Back Directory | [Appearance]
LIGHT PINK TO LIGHT BROWN CRYSTALLINE POWDER | [Melting point ]
181-190 °C (dec.)(lit.)
| [Boiling point ]
401.58°C (rough estimate) | [density ]
1.1027 (rough estimate) | [refractive index ]
1.5680 (estimate) | [form ]
powder to crystaline | [pka]
8.91±0.50(Predicted) | [color ]
White to Brown | [EPA Substance Registry System]
1,1-Methylenedi-2-naphthol (1096-84-0) |
| Hazard Information | Back Directory | [Chemical Properties]
LIGHT PINK TO LIGHT BROWN CRYSTALLINE POWDER | [Uses]
Squoxin (ST1859) is an antiamyloid agent that specifically binds to Aβ1-42 and prevents the aggregation and fibril formation of Aβ. Squoxin crosses the blood-brain barrier (BBB) and has anthelmintic activity and anti-inflammatory properties[1]. | [References]
[1] Martin Bauer, et al. A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease. Clin Pharmacol Ther. 2006 Sep;80(3):216-27. DOI:10.1016/j.clpt.2006.05.007 |
| Safety Data | Back Directory | [Safety Statements ]
22-24/25 | [WGK Germany ]
3
| [RTECS ]
QL4400000
| [HS Code ]
2907.29.9000 | [Toxicity]
mouse,LD50,intraperitoneal,1gm/kg (1000mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 381, 1978. |
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