| Identification | Back Directory | [Name]
TSQ | [CAS]
109628-27-5 | [Synonyms]
TSQ
Nsc 120213
N-(6-METHOXY-8-QUINOLYL)-P-TOLUENESULFONAMIDE
n-(6-methoxy-8-quinolyl)-4-toluenesulfonamide
P-toluenesulfonamide,n-(6-methoxy-8-quinolyl)-
N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide
(N-6-METHOXY-8-QUINOLINYL)-4-METHYLBENZENE SULFONAMIDE
Benzenesulfonamide, N-(6-methoxy-8-quinolinyl)-4-methyl- | [Molecular Formula]
C17H16N2O3S | [MDL Number]
MFCD00467847 | [MOL File]
109628-27-5.mol | [Molecular Weight]
328.39 |
| Chemical Properties | Back Directory | [Melting point ]
133–134 ℃ | [storage temp. ]
-20°C Freezer | [solubility ]
Soluble in ethanol, methanol | [form ]
crystals | [color ]
White | [λmax]
334 nm | [Biological Applications]
Zinc indicator; early diagnosis of prostate cancer; treating age-related macular degeneration (AMD),amyloidosis disorders,autoimmune diseases,herpes virus infection | [InChI]
1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3 | [InChIKey]
HKRNYOZJJMFDBV-UHFFFAOYSA-N | [SMILES]
O=S(C1=CC=C(C)C=C1)(NC2=C3C(C=CC=N3)=CC(OC)=C2)=O |
| Hazard Information | Back Directory | [Description]
N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is a membrane-permeant Zn2+ indicator. | [Uses]
Determn of extracellular and intracellular Zn2+ levels in biological systems. | [Uses]
Zn+ selective probe in the presence of Mg+ and Ca+. | [Biochem/physiol Actions]
TSQ (6-methoxy-8-p-toluenesulfonamido-quinoline) is a cell penetrant and specific fluorescent zinc sensor that preferentially accumulates in islet cells in a zinc content dependent manner. TSQ is commonly used to assess isolated islet purity. | [Excitation / Emission Maximum]
565 nm/590 nm |
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Sigma-Aldrich
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Energy Chemical
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